- Basic information
- CohesinDB ID: CDBP00417451
- Locus: chr21-33715952-33716503
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Data sourse: GSE206145, ENCSR247LSH, ENCSR153HNT, ENCSR767DFK
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Cell type: K-562, A-549, HEK293T
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
88% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 39%,
"15_Quies": 38%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF660, SOX2, PATZ1, FOXA1, PBX2, ZFP64, PRDM1, IKZF3, MZF1, ELF1, ZNF121, TRIM28, OCA2, CTCF, EP300, E4F1, ZBTB20, IRF4, ZNF674, TFAP2C, EED, GLIS1, POU2F2, CHD8, POU5F1, ZNF263, BRD3, CTBP1, ZSCAN21, ZBTB17, ZBTB48, ZNF317, ERG2, SP4, TBP, ERG, ONECUT1, MYC, ZNF84, ZNF2, NKX2-1, GABPA, XRCC5, IKZF1, RCOR1, ZNF343, NR2F6, ZBTB11, EZH2, KLF8, GABPB1, ELF4, SPI1, IRF1, GATA2, SIX2, NR2C2, ZNF76, ZNF554, HDAC1, ZNF335, ZFX, SMAD3, ZNF770, ERG3, ZNF549, PRDM10, ZNF18, ZNF35, ZNF384, CDK6, OSR2, ZNF184, SP3, ZEB2, ZNF518A, NR2C1, SP2, ZNF10, CDK8, MED1, TERF1, ZNF331, NUP98-HOXA9, RBM22, BCL11A, TFAP2A, PHIP, FOXP1, PRDM6, ZNF394, PPARG, FOXA2, ZNF600, ZNF692, ZSCAN16, ZNF574, CDK9, ZNF580, YY1, RELA, ZNF830, HIF1A, OTX2, MAX, GATA1, ZNF143, ZNF592, SP7, ZNF512, NR2F1, ZBTB6, ZSCAN22, EGR2, BRD2, BHLHE40, AR, ZBTB40, ZNF324, ZBTB42, ZNF366, EGR1, ZBTB26, NCOR1, NOTCH3, BRD4, MAZ, ZSCAN23, ZFP42
- Target gene symbol (double-evidenced CRMs): MRPS6,ITSN1,HUNK,ATP5PO,SON,RCAN1,AP000311.1,SLC5A3,CRYZL1,DONSON
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 9
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000142149,
ENSG00000159140,
ENSG00000159147,
ENSG00000249209,
ENSG00000205758,
ENSG00000205726,
ENSG00000241837,
ENSG00000243927,
ENSG00000198743,
ENSG00000159200,
- Related loop:
chr21:31950000-31975000~~chr21:33700000-33725000,
chr21:33550000-33575000~~chr21:33700000-33725000,
chr21:33575000-33600000~~chr21:33700000-33725000,
chr21:33700000-33725000~~chr21:33875000-33900000,
chr21:33700000-33725000~~chr21:33900000-33925000,
chr21:33700000-33725000~~chr21:34100000-34125000,
chr21:33700000-33725000~~chr21:34200000-34225000,
chr21:33700000-33725000~~chr21:34250000-34275000,
chr21:33700000-33725000~~chr21:34325000-34350000,
chr21:33700000-33725000~~chr21:34525000-34550000,
chr21:33700000-33725000~~chr21:34600000-34625000,