- Basic information
- CohesinDB ID: CDBP00417452
- Locus: chr21-33717558-33717807
-
Data sourse: GSE206145, GSE206145-NatGen2015, GSE67783
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Cell type: RPE, Fibroblast, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21,SA2
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
88% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"5_TxWk": 53%,
"15_Quies": 45%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: WT1, ZFX
- Target gene symbol (double-evidenced CRMs): ITSN1,DONSON,CRYZL1,MRPS6,RCAN1,ATP5PO,AP000311.1,HUNK,SLC5A3,SON
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 27
- Number of somatic mutations (non-coding): 3
- Related genes and loops
- Related gene:
ENSG00000142149,
ENSG00000159140,
ENSG00000159147,
ENSG00000249209,
ENSG00000205758,
ENSG00000205726,
ENSG00000241837,
ENSG00000243927,
ENSG00000198743,
ENSG00000159200,
- Related loop:
chr21:31950000-31975000~~chr21:33700000-33725000,
chr21:33550000-33575000~~chr21:33700000-33725000,
chr21:33575000-33600000~~chr21:33700000-33725000,
chr21:33700000-33725000~~chr21:33875000-33900000,
chr21:33700000-33725000~~chr21:33900000-33925000,
chr21:33700000-33725000~~chr21:34100000-34125000,
chr21:33700000-33725000~~chr21:34200000-34225000,
chr21:33700000-33725000~~chr21:34250000-34275000,
chr21:33700000-33725000~~chr21:34325000-34350000,
chr21:33700000-33725000~~chr21:34525000-34550000,
chr21:33700000-33725000~~chr21:34600000-34625000,