- Basic information
- CohesinDB ID: CDBP00417464
- Locus: chr21-33751050-33751840
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Data sourse: GSE138405, GSE206145-NatGen2015, ENCSR153HNT, ENCSR879KXD
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Cell type: K-562, Hela-Kyoto, Fibroblast
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"5_TxWk": 53%,
"15_Quies": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, PGR, MEIS2, FOXA1, PBX2, ATF3, ATF4, SMARCE1, MITF, TRIM28, E2F5, NFE2L2, USF2, JUN, CTCF, EP300, E4F1, MNT, DPF2, E2F6, TRIM24, SOX6, RAD51, E2F1, TEAD4, ZNF175, EHMT2, CHD8, MYCN, TOP2A, ID3, ZBTB48, ZSCAN5A, NBN, ERG, MYC, SMARCA4, ARID1B, XRCC5, IKZF1, NFE2, RCOR1, ZNF639, NR2F6, CEBPB, KMT2A, GATA2, ZNF644, SREBF1, EP400, NCOA2, ATF1, MAFG, HDAC1, LDB1, POU4F2, TWIST1, SMARCC1, ZNF384, RUNX2, GATA4, PBX4, ARNT, BACH1, HMBOX1, NFYA, CBFA2T3, FOXM1, NR2C1, MED1, C11orf30, L3MBTL2, STAT5A, NUP98-HOXA9, USF1, BCL11A, MAFK, ZBTB7A, PRDM6, CBX3, CREM, ZNF692, MAFF, HOXB13, RELA, JUNB, HIF1A, OTX2, MGA, MAX, ZNF143, GATA1, ZNF592, NR2F2, NR2F1, PKNOX1, ZNF334, AR, ZBTB40, RNF2, NCOR1, JUND, ILF3, BRD4, ZNF316
- Target gene symbol (double-evidenced CRMs): AP000311.1,ATP5PO,ITSN1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 88
- Number of somatic mutations (non-coding): 8
- Related genes and loops