Deatailed information for cohesin site CDBP00417470

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  • Basic information
  • CohesinDB ID: CDBP00417470
  • Locus: chr21-33760388-33764540
  • Data sourse: GSE206145-GSE177045, ENCSR230ZWH, GSE72082, ENCSR000BSB, ENCSR501LQA, GSE126634, ENCSR760NPX, ENCSR000BLY, ENCSR150EFU, GSE103477, GSE25021, ENCSR330ELC, GSE108869, ENCSR917QNE, ENCSR000EFJ, ENCSR000BTU, GSE165895, GSE67783, ENCSR000BKV, GSE86191, GSE138405, GSE101921, ENCSR806UKK, GSE206145-NatGen2015, GSE138105, GSE130135, ENCSR199XBQ, ENCSR703TNG, GSE116344, ENCSR895JMI, GSE98367, ENCSR193NSH, ENCSR768DOX, ENCSR879KXD, GSE206145, GSE85526, ENCSR981FDC, ENCSR247LSH, ENCSR620NWG, ENCSR748MVX, ENCSR767DFK, ENCSR495WGO, ENCSR984DZW, GSE97394, ENCSR217ELF, ENCSR000BTQ, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, GSE131956, GSE129526, ENCSR000HPG, ENCSR676MJK, ENCSR335RKQ, ENCSR054FKH, ENCSR000EDE, ENCSR153HNT, GSE68388, GSE83726, GSE126990, ENCSR000ECS
  • Cell type: RH4, SLK, Liver, HuCC-T1, RPE, Fibroblast, HEKn, Ishikawa, HeLa-S3, IMR-90, K-562, HFFc6, GBM39, SK-N-SH, HAP1, Macrophage, HUES64, MCF-7, THP-1, Hela-Kyoto, HCT-116, HEK293T, Hep-G2, A-549, HCAEC, HSPC
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 32% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.700
  • Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True
  • Compartment: 90% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "5_TxWk": 42%, "7_Enh": 30%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, FOXA1, HLF, RXRB, ZBTB44, IKZF3, TEAD1, ZNF121, ZNF561, ZNF577, E4F1, SOX5, ZNF528, KMT2B, GATAD2A, POU5F1, BRD3, ZNF263, CTBP1, STAT1, SAP130, ERG, ZBTB21, ZBTB8A, SMARCA4, FOXK2, UBN1, RCOR1, NR2F6, CEBPB, CREB1, GABPB1, ZHX2, ELF4, MIXL1, KLF17, GATA2, ZNF644, FLI1, HCFC1, DRAP1, EP400, RUNX1, CEBPA, HDAC1, NKX2-2, ZNF707, ZNF654, SMARCC1, PRDM10, ELK1, ATF2, GMEB1, PIAS1, NR1H2, C11orf30, EVI1, IKZF5, ARID2, AFF1, ELL2, CBX3, CREM, SS18, NFATC1, ZSCAN16, WT1, MEF2C, NEUROD1, JUNB, TCF4, BATF, ZNF333, ZFP69B, KLF4, ZKSCAN8, ELF3, ARID4B, EGLN2, ZNF366, HSF1, NCOR1, ILF3, ZNF316, FOSL1, SMARCA2, ZNF660, ZNF101, PBX2, ATF3, ZFP64, CBFB, ZNF273, ZSCAN4, TP63, MAF, JMJD1C, ELF1, ZNF573, KLF10, CTCF, JUN, MNT, ZBTB20, DPF2, IRF4, ZNF280A, TFAP2C, ZSCAN21, ZBTB17, ZBTB48, SRF, NBN, ZNF329, ZNF2, TSHZ1, HOMEZ, RXRA, NKX3-1, VDR, NR3C1, ESRRA, KMT2A, KLF8, GRHL2, ZNF146, SMARCA5, NFIL3, THAP11, EZH2phosphoT487, AFF4, SOX13, ZNF770, ZMIZ1, DAXX, ARNT, BACH1, ZEB2, HMBOX1, PBX3, MAFB, ZNF10, HMGXB4, TEAD3, ZXDB, ZNF680, KLF9, TBX5, USF1, SP1, BCL11A, ATF7, PRDM6, ZNF623, SMC3, STAG1, STAG2, ZNF394, MTA3, MAFF, ZNF580, ZKSCAN1, KDM1A, ZIC2, GATA3, TAL1, ZNF143, MTA1, TP53, NFKB1, BRD2, KAT8, RNF2, BRD4, JUND, ZSCAN23, PGR, CBX5, SOX2, PATZ1, UBTF, TFAP4, CHD7, ZNF189, SMARCE1, MZF1, KLF6, NFE2L2, ZNF217, ESR1, KLF1, ZNF695, ZNF260, SOX4, TRIM24, RFX5, GLIS1, ZNF778, ZSCAN5A, TBP, HOXC5, SMARCC2, ETS1, MYC, ARID1B, NKX2-1, GABPA, STAT3, EZH2, NFE2L1, MRTFA, SPI1, HDAC2, GATAD2B, TAF9B, ZNF76, ZNF554, ETV5, SIN3A, ZBTB12, ERG3, CREBBP, ZNF384, ZNF35, ZNF133, RARA, ZNF518A, CDK8, ZEB1, SPDEF, SUPT16H, NCOA1, ZNF22, RBM22, MAFK, HNF4A, NR4A1, REST, ARID1A, ZHX1, PPARG, ZNF692, GTF2B, ZNF30, ZNF574, ZNF318, RELA, CHAMP1, MAX, ZNF592, NEUROG2, NR2F1, TCF7L2, PKNOX1, MYOD1, AR, YAP1, ZNF324, DMAP1, AHR, FOSL2, ZNF391, HMG20A, ZSCAN5C, E2F7, INSM2, NFIC, ZNF362, PRDM1, HDAC3, ZNF629, TRIM28, ZNF557, ETV1, RCOR2, HNF1B, TCF12, EP300, BAF155, E2F1, SMC1, TEAD4, FOXA3, EHMT2, CHD8, MYCN, ID3, ARID3A, ZNF300, ASCL1, RAD21, PROX1, ZNF614, NFE2, ZNF639, ZNF750, FEZF1, EHF, IRF1, ZGPAT, MRTFB, ATF1, SMC1A, MAFG, ZNF335, ZFX, SMAD3, TWIST1, RUNX2, ZSCAN30, GATA4, OSR2, ZNF184, GR, NRF1, PBX4, NR2C1, FOS, MED1, ZNF558, KLF16, NIPBL, ZBTB7A, PHIP, TCF3, FOXA2, ZNF600, FOXF1, CDK9, HOXB13, YY1, HIF1A, OTX2, HAND2, CEBPG, SP7, NR2F2, ZNF213, ZNF843, ZFP28, BHLHE40, TAF1, ZBTB40, ZBTB42, CLOCK, MAZ, ZNF24
  • Target gene symbol (double-evidenced CRMs): ATP5PO,CRYZL1,ITSN1,AP000311.1
  • Function elements
  • Human SNPs: Red_cell_distribution_width
  • Number of somatic mutations (coding): 418
  • Number of somatic mutations (non-coding): 0
  • Related genes and loops
  • Related gene: ENSG00000249209, ENSG00000205758, ENSG00000205726, ENSG00000241837,
  • Related loop: chr21:33640618-33644548~~chr21:33759990-33762515, chr21:33640920-33645557~~chr21:33759827-33762711, chr21:33640934-33645075~~chr21:33759935-33762613, chr21:33650000-33675000~~chr21:33750000-33775000, chr21:33750000-33775000~~chr21:33875000-33900000, chr21:33750000-33775000~~chr21:33900000-33925000,
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