- Basic information
- CohesinDB ID: CDBP00417475
- Locus: chr21-33771637-33772371
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Data sourse: GSE206145, GSE206145-NatGen2015, GSE67783, ENCSR153HNT
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Cell type: K-562, Fibroblast, HSPC, RPE
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"4_Tx": 55%,
"5_TxWk": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, TRP47, PGR, CHD8, PPARG, TBL1X, MYCN, POU5F1, ID3, SIN3A, XBP1, ZBTB48, WT1, STAT1, TET2, ZBTB33, ZNF300, YY1, RELA, ATF3, MYC, CDK6, GATA4, SP140, ARNT, GATA3, ZNF197, ZNF8, MAX, GATA1, IKZF1, CEBPB, TRIM28, NR2F1, EZH2, SETDB1, CTCF, RBM22, GSPT2, AR, GATA2, ZNF146, HSF1, NCOR1, HNRNPLL, BRD4, NOTCH3, MAZ, SMC3, ETV5, AHR
- Target gene symbol (double-evidenced CRMs): AP000311.1,ITSN1,ATP5PO
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 627
- Number of somatic mutations (non-coding): 57
- Related genes and loops
- Related gene:
ENSG00000249209,
ENSG00000205726,
ENSG00000241837,
- Related loop:
chr21:33650000-33675000~~chr21:33750000-33775000,
chr21:33675000-33700000~~chr21:33775000-33800000,
chr21:33750000-33775000~~chr21:33875000-33900000,
chr21:33750000-33775000~~chr21:33900000-33925000,
chr21:33775000-33800000~~chr21:33875000-33900000,
chr21:33775000-33800000~~chr21:34100000-34125000,
chr21:33775000-33800000~~chr21:34250000-34275000,