- Basic information
- CohesinDB ID: CDBP00417477
- Locus: chr21-33773678-33774027
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Data sourse: GSE67783, ENCSR153HNT, GSE86191
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Cell type: K-562, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 61%,
"4_Tx": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, FOSL1, PGR, MAFG, CHD8, FOXA2, NKX2-2, PAF1, ZFX, MEIS2, ZNF600, ZBTB48, FOXA1, ZNF770, PBX2, HOXB13, ERG, RELA, ZNF329, ATF3, MYC, SMARCA4, ARID1B, GR, ARNT, HIF1A, GRHL3, GATA3, TAL1, STAT3, NKX3-1, GATA1, FOS, IKZF1, ZNF143, NR2F6, TEAD1, PIAS1, ZNF217, ESR1, LMO2, GRHL2, SPI1, BAF155, BCL11A, HNF4A, AR, GATA2, EGLN2, RBM25, FLI1, ZNF777, RNF2, ASH2L, JUND, BRD4, FOXP1, E2F1, ZNF554, PDX1, TFAP2C, EED
- Target gene symbol (double-evidenced CRMs): AP000311.1,ITSN1,ATP5PO
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 44
- Number of somatic mutations (non-coding): 4
- Related genes and loops
- Related gene:
ENSG00000249209,
ENSG00000205726,
ENSG00000241837,
- Related loop:
chr21:33650000-33675000~~chr21:33750000-33775000,
chr21:33675000-33700000~~chr21:33775000-33800000,
chr21:33750000-33775000~~chr21:33875000-33900000,
chr21:33750000-33775000~~chr21:33900000-33925000,
chr21:33775000-33800000~~chr21:33875000-33900000,
chr21:33775000-33800000~~chr21:34100000-34125000,
chr21:33775000-33800000~~chr21:34250000-34275000,