- Basic information
- CohesinDB ID: CDBP00417479
- Locus: chr21-33778597-33778946
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Data sourse: GSE206145, GSE206145-NatGen2015
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Cell type: RPE, Fibroblast
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 55%,
"15_Quies": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: KAT2B, ONECUT1, FOXA2, POU5F1, ZBTB48, SETDB1, ZBTB33, ZNF280A, BAHD1, ZNF143
- Target gene symbol (double-evidenced CRMs): SLC5A3,ITSN1,AP000311.1,MRPS6,ATP5PO
- Function elements
- Human SNPs: Mean_corpuscular_volume
- Number of somatic mutations (coding): 22
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000249209,
ENSG00000205726,
ENSG00000241837,
ENSG00000243927,
ENSG00000198743,
- Related loop:
chr21:33650000-33675000~~chr21:33750000-33775000,
chr21:33675000-33700000~~chr21:33775000-33800000,
chr21:33750000-33775000~~chr21:33875000-33900000,
chr21:33750000-33775000~~chr21:33900000-33925000,
chr21:33775000-33800000~~chr21:33875000-33900000,
chr21:33775000-33800000~~chr21:34100000-34125000,
chr21:33775000-33800000~~chr21:34250000-34275000,