- Basic information
- CohesinDB ID: CDBP00417489
- Locus: chr21-33798590-33800042
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Data sourse: ENCSR230ZWH, GSE138405, ENCSR000EDE, GSE126990, GSE108869, ENCSR000ECS, ENCSR917QNE
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Cell type: Liver, HeLa-S3, Hela-Kyoto
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SMC3,Rad21,SA2,SA1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 47%,
"4_Tx": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, CHD8, MAFG, ZNF316, MYCN, SOX2, ZFX, SIN3A, GTF2B, ZSCAN5A, STAT1, FOXA1, HOXB13, ERG, RELA, CDK6, PRDM1, NKX2-1, GATA1, NFE2, MED1, TLE3, TRIM28, ETV1, PIAS1, EZH2, ESR1, PKNOX1, C11orf30, GRHL2, ZNF334, RBM22, BAF155, AR, GATA6, BRD4, FOXP1, NCOA2, AHR, EED
- Target gene symbol (double-evidenced CRMs): ITSN1,DONSON,ATP5PO,SON,CRYZL1,IFNAR2,AP000311.1,SLC5A3,MRPS6,AP000295.1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 363
- Number of somatic mutations (non-coding): 29
- Related genes and loops
- Related gene:
ENSG00000249624,
ENSG00000159110,
ENSG00000159140,
ENSG00000159147,
ENSG00000249209,
ENSG00000205758,
ENSG00000205726,
ENSG00000241837,
ENSG00000243927,
ENSG00000198743,
- Related loop:
chr21:33200000-33225000~~chr21:33800000-33825000,
chr21:33550000-33575000~~chr21:33800000-33825000,
chr21:33625000-33650000~~chr21:33800000-33825000,
chr21:33640623-33644540~~chr21:33801019-33802509,
chr21:33675000-33700000~~chr21:33775000-33800000,
chr21:33675000-33700000~~chr21:33800000-33825000,
chr21:33775000-33800000~~chr21:33875000-33900000,
chr21:33775000-33800000~~chr21:34100000-34125000,
chr21:33775000-33800000~~chr21:34250000-34275000,