- Basic information
- CohesinDB ID: CDBP00417494
- Locus: chr21-33811054-33812794
-
Data sourse: GSE67783, GSE98367, ENCSR404BPV, GSE206145-NatGen2015, ENCSR917QNE
-
Cell type: Fibroblast, Neurons-H1, Liver, HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SMC1,Mau2,SMC3
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: non-Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"5_TxWk": 48%,
"7_Enh": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: CDK9-HEXIM1, CHD8, PPARG, SMC1A, LDB1, FOXA2, NKX2-2, TOP2A, GTF2B, ZBTB48, SMARCC1, YY1, RELA, ZNF384, RUNX2, MYC, RAD21, TAL1, MAFB, NKX3-1, GATA1, ZNF143, NFE2, MED1, CEBPB, NR2F2, KMT2A, MYB, CTCF, JUN, MAFK, BCL11A, EP300, SPI1, SP1, AR, RXR, REST, IRF4, SCRT1, BRD4, PDX1, RBPJ
- Target gene symbol (double-evidenced CRMs): AP000295.1,ITSN1,AP000311.1,DONSON,SON,CRYZL1,IFNAR2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 517
- Number of somatic mutations (non-coding): 33
- Related genes and loops
- Related gene:
ENSG00000249624,
ENSG00000159110,
ENSG00000159140,
ENSG00000159147,
ENSG00000249209,
ENSG00000205758,
ENSG00000205726,
- Related loop:
chr21:33200000-33225000~~chr21:33800000-33825000,
chr21:33550000-33575000~~chr21:33800000-33825000,
chr21:33625000-33650000~~chr21:33800000-33825000,
chr21:33675000-33700000~~chr21:33800000-33825000,