- Basic information
- CohesinDB ID: CDBP00417495
- Locus: chr21-33813937-33814344
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Data sourse: GSE67783, ENCSR153HNT, GSE98367
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Cell type: K-562, HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"4_Tx": 50%,
"5_TxWk": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: CHD8, POU5F1, ZFX, WT1, ZBTB48, ZSCAN5A, SUZ12, RELA, ZNF384, SP140, ARNT, NKX2-1, ZNF143, DNMT3B, ESR1, TP53, CTCF, RBM22, SPI1, SMC3, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): DONSON,IFNAR2,CRYZL1,ITSN1,AP000311.1,AP000295.1,SON
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 220
- Number of somatic mutations (non-coding): 20
- Related genes and loops
- Related gene:
ENSG00000249624,
ENSG00000159110,
ENSG00000159140,
ENSG00000159147,
ENSG00000249209,
ENSG00000205758,
ENSG00000205726,
- Related loop:
chr21:33200000-33225000~~chr21:33800000-33825000,
chr21:33550000-33575000~~chr21:33800000-33825000,
chr21:33625000-33650000~~chr21:33800000-33825000,
chr21:33675000-33700000~~chr21:33800000-33825000,