Deatailed information for cohesin site CDBP00417497

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  • Basic information
  • CohesinDB ID: CDBP00417497
  • Locus: chr21-33816580-33816843
  • Data sourse: GSE116344, GSE206145-NatGen2015, GSE67783
  • Cell type: Fibroblast, RH4, HSPC
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 1% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.967
  • Subunit: SA1,Rad21,SA2
  • CTCF binding site: non-CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: non-Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 90% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): False
  • Chromatin annotation: "4_Tx": 47%, "5_TxWk": 30%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: NFIA, FOSL1, ZNF391, PGR, ZSCAN5C, ZNF660, SOX2, XBP1, PATZ1, FOXA1, PBX2, ZNF28, ZFHX2, ZNF596, INSM2, NFIC, ATF3, ZFP64, ZBTB44, PRDM1, IKZF3, ATF4, ZNF189, MZF1, ZSCAN4, MITF, ZNF467, ZNF629, KLF5, TRIM28, ZNF121, KLF10, ESR1, ZNF561, ZNF524, CTCF, TCF12, ZNF577, EP300, KLF1, JUN, LMO1, ZBTB20, MNT, DPF2, PRDM4, IRF4, TRIM24, SOX6, DEK, E2F4, ZNF423, E2F1, ZNF528, ZNF350, KLF3, TEAD4, GTF2F1, TFAP2C, GLIS1, POU2F2, CHD8, NANOG, ZSCAN5D, MYCN, BRD3, RUNX1T1, KDM4C, ZNF263, ZNF778, ZSCAN21, ZBTB17, ZBTB48, ZSCAN5A, STAT1, CTBP1, SRF, ZMYND8, ERG2, TBP, ERG, ZBTB21, ZBTB8A, ZNF341, MYC, EZH1, SMARCA4, TSHZ1, ZNF2, RAD21, FOXP2, ARID1B, GABPA, STAT3, ZNF398, IKZF1, NFE2, HNRNPH1, DNMT3B, ZNF639, RCOR1, NR3C1, CEBPB, ESRRA, KMT2A, KLF8, BMPR1A, FEZF1, SPI1, ZNF664, INTS13, GATA2, FLI1, ZNF490, MRTFB, ZNF76, ZNF554, ATF1, RUNX1, SMC1A, CEBPA, LDB1, AFF4, ZFX, ZNF534, POU4F2, ZNF335, SMAD3, ZBTB12, REPIN1, ZNF770, ERG3, TET2, ZNF513, ZNF18, PRDM10, SMARCC1, CREBBP, ZNF35, NOTCH1, BRD9, ZSCAN30, OSR2, ZNF184, ARNT, ATF2, ZEB2, ZNF518A, FOXM1, CBFA2T3, ZNF10, FOS, CDK8, MED1, ZEB1, ZXDB, MYB, ZNF680, SCRT2, ZNF558, PIAS1, SMAD1, KLF9, L3MBTL2, EVI1, SETDB1, KLF16, RBM22, USF1, NUP98-HOXA9, BCL11A, TFAP2A, ZBTB7A, OVOL3, ZHX1, ATF7, PHIP, TCF3, PRDM6, SMC3, ELL2, ZNF34, STAG1, ZNF394, PPARG, TBL1X, MTA3, CBX3, CREM, SS18, ZNF600, ZNF692, ZSCAN16, WT1, ZNF30, ZNF574, CDK9, ZNF580, KLF7, YY1, RELA, TARDBP, JUNB, ZNF610, SP140, ZIC2, HIF1A, ZFP36, ZNF519, TAL1, MAX, ZNF449, ZNF143, GATA1, ZFP69B, BCL11B, SP7, GFI1B, ZNF592, NR2F2, NR2F1, TCF7L2, ZNF768, TP53, ZNF213, PKNOX1, ZNF334, NFKB1, BCL6B, EGR2, ZSCAN22, BRD2, ZNF843, BHLHE40, AR, RXR, ZNF324, ZNF366, ZBTB42, HSF1, ZBTB26, NCOR1, BRD4, ZNF248, SCRT1, JUND, RNF2, MAZ, ZSCAN23, ZNF24, ZFP42, AHR
  • Target gene symbol (double-evidenced CRMs): IFNAR2,SON,ITSN1,DONSON,AP000295.1,AP000311.1,CRYZL1
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 11
  • Number of somatic mutations (non-coding): 1
  • Related genes and loops
  • Related gene: ENSG00000249624, ENSG00000159110, ENSG00000159140, ENSG00000159147, ENSG00000249209, ENSG00000205758, ENSG00000205726,
  • Related loop: chr21:33200000-33225000~~chr21:33800000-33825000, chr21:33550000-33575000~~chr21:33800000-33825000, chr21:33625000-33650000~~chr21:33800000-33825000, chr21:33675000-33700000~~chr21:33800000-33825000,
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