- Basic information
- CohesinDB ID: CDBP00417501
- Locus: chr21-33824293-33824912
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Data sourse: ENCSR000BLD, ENCSR000EEG, ENCSR230ZWH, GSE86191, GSE116344, ENCSR000EDW, ENCSR917QNE
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Cell type: H1-hESC, RH4, HCT-116, Hep-G2, Liver
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SMC3,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 48%,
"15_Quies": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: POU5F1, ZFX, ZBTB48, WT1, ZNF205, RELA, ZNF384, ZNF133, RUNX2, RAD21, ZIC2, RXRA, STAT3, XRCC5, ZBTB6, MYOD1, CTCF, RBM22, HNF4A, RNF2, BRD4, SMC3, RBPJ
- Target gene symbol (double-evidenced CRMs): CRYZL1,AP000311.1,SON,AP000295.1,IFNAR2,ITSN1,DONSON
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 10
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000249624,
ENSG00000159110,
ENSG00000159140,
ENSG00000159147,
ENSG00000249209,
ENSG00000205758,
ENSG00000205726,
- Related loop:
chr21:33200000-33225000~~chr21:33800000-33825000,
chr21:33550000-33575000~~chr21:33800000-33825000,
chr21:33625000-33650000~~chr21:33800000-33825000,
chr21:33625000-33650000~~chr21:33825000-33850000,
chr21:33675000-33700000~~chr21:33800000-33825000,
chr21:33825000-33850000~~chr21:38075000-38100000,
chr21:7800000-7825000~~chr21:33825000-33850000,