- Basic information
- CohesinDB ID: CDBP00417502
- Locus: chr21-33825760-33826294
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Data sourse: ENCSR000EFJ, ENCSR000HPG, GSE206145, GSE206145-NatGen2015, GSE116344
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Cell type: RPE, Fibroblast, RH4, IMR-90
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SA2,Mau2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 53%,
"7_Enh": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, PGR, CHD8, FOXA2, MYCN, SOX2, CBX8, SMARCC1, BMI1, RUNX2, MYC, SMARCA4, NFIC, RAD21, ZFP36, SMARCE1, STAT3, MED1, NR3C1, TEAD1, JUN, RBM22, TCF12, AR, GATA2, FOSL2, RNF2, MXI1, BRD4, MAZ, EED
- Target gene symbol (double-evidenced CRMs): AP000311.1,CRYZL1,ITSN1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 50
- Number of somatic mutations (non-coding): 5
- Related genes and loops
- Related gene:
ENSG00000249209,
ENSG00000205758,
ENSG00000205726,
- Related loop:
chr21:33200000-33225000~~chr21:33800000-33825000,
chr21:33550000-33575000~~chr21:33800000-33825000,
chr21:33625000-33650000~~chr21:33800000-33825000,
chr21:33625000-33650000~~chr21:33825000-33850000,
chr21:33675000-33700000~~chr21:33800000-33825000,
chr21:33825000-33850000~~chr21:38075000-38100000,
chr21:7800000-7825000~~chr21:33825000-33850000,