- Basic information
- CohesinDB ID: CDBP00417503
- Locus: chr21-33828224-33828582
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Data sourse: GSE67783, ENCSR153HNT, GSE86191
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Cell type: K-562, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 37%,
"4_Tx": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, ZSCAN5D, MYCN, TOP2A, ZFX, XBP1, ZBTB48, ZSCAN5A, WT1, ZNF662, SUZ12, RELA, RUNX2, SP140, HIF1A, MECOM, DNMT3B, MED1, NR3C1, EZH2, KDM5B, ESR1, OCA2, CTCF, RBM22, AR, GATA2, ZNF366, BRD4, SMC3
- Target gene symbol (double-evidenced CRMs): AP000311.1,CRYZL1,ITSN1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 20
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000249209,
ENSG00000205758,
ENSG00000205726,
- Related loop:
chr21:33200000-33225000~~chr21:33800000-33825000,
chr21:33550000-33575000~~chr21:33800000-33825000,
chr21:33625000-33650000~~chr21:33800000-33825000,
chr21:33625000-33650000~~chr21:33825000-33850000,
chr21:33675000-33700000~~chr21:33800000-33825000,
chr21:33825000-33850000~~chr21:38075000-38100000,
chr21:7800000-7825000~~chr21:33825000-33850000,