- Basic information
- CohesinDB ID: CDBP00417505
- Locus: chr21-33831449-33832606
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Data sourse: GSE138405, GSE67783, ENCSR153HNT, GSE86191
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Cell type: K-562, Hela-Kyoto, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"4_Tx": 43%,
"5_TxWk": 34%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, TRIM25, CBFA2T2, SMC1A, CEBPA, POU5F1, MYCN, ZNF496, ZFX, ZNF600, ZNF317, XBP1, WT1, ZSCAN5A, ZBTB48, NME2, FOXF1, TET2, SUZ12, YY1, RELA, ATF3, MYC, SP140, GRHL3, NKX2-1, MAF1, CHD1, DNMT3B, ZNF467, PLAG1, CEBPB, SRSF3, TEAD1, ESR1, OCA2, CTCF, RBM22, AR, REST, HEXIM1, FLI1, MAZ, STAG1
- Target gene symbol (double-evidenced CRMs): AP000311.1,ITSN1,CRYZL1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 60
- Number of somatic mutations (non-coding): 6
- Related genes and loops