Deatailed information for cohesin site CDBP00417512

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  • Basic information
  • CohesinDB ID: CDBP00417512
  • Locus: chr21-33844101-33846801
  • Data sourse: ENCSR338DUC, GSE67783, GSE86191, GSE131956, GSE126634, ENCSR404BPV, GSE206145, GSE206145-NatGen2015, ENCSR198ZYJ, ENCSR153HNT, GSE165895
  • Cell type: RPE, Fibroblast, HCT-116, Hep-G2, Neurons-H1, GBM39, HSPC, K-562, HAP1, HFFc6
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 4% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.889
  • Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: non-Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 90% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "15_Quies": 35%, "7_Enh": 28%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, NFIA, TRIM25, PGR, FOSL1, SMARCA2, HMG20A, SOX2, XBP1, PATZ1, FOXA1, ZNF28, ZFHX2, HDGF, ATF3, NFIC, CHD7, ZNF189, SMARCE1, PAX5, TP63, ZNF467, MYOG, ZNF629, TEAD1, TRIM28, ZNF26, SNAI2, KLF10, ESR1, OCA2, CTCF, TCF12, JUN, EP300, MNT, SOX5, DPF2, SOX4, DMAP1, ZNF528, TEAD4, GATAD2A, RBPJ, EED, TFAP2C, GLIS1, POU2F2, CHD8, ZNF263, MYCN, RUNX1T1, ID3, KDM4C, POU5F1, ZSCAN21, ZBTB17, ZBTB48, ZSCAN5A, SAP130, NBN, ERG2, ZNF300, ERG, ASCL1, MYC, SMARCA4, FOXP2, RAD21, GRHL3, NKX2-1, GABPA, STAT3, XRCC5, PRDM14, IKZF1, MIER3, DNMT3B, ZNF398, ZNF639, NR3C1, CEBPB, KMT2A, EZH2, GRHL2, GABPB1, ZHX2, SPI1, KLF17, HDAC2, GATA2, ZNF644, GATAD2B, MXD3, FLI1, MXI1, SMARCA5, RELB, MRTFB, PTBP1, ETV5, RUNX1, BCL6, SOX13, ZFX, POU4F2, SIN3A, SMAD3, TET2, ERG3, CBX8, SP5, TRIM22, SMARCC1, RARA, CREBBP, ZNF169, OSR2, ZNF184, ARNT, NRF1, PBX4, ZNF48, PRDM9, SMAD4, PBX3, FOXM1, FOS, CDK8, SMARCB1, MED1, TEAD3, ZNF264, MYB, ZNF3, KLF9, SETDB1, RBM22, USF1, TFAP2A, HNF4A, IKZF5, REST, ARID1A, ZBTB7A, ATF7, SMC3, ELL2, STAG1, MLLT1, NFATC3, ZNF316, MIER2, ZNF600, WT1, ZBTB33, KDM1A, YY1, RELA, TARDBP, JUNB, MCM3, SP140, ZIC2, ZFP36, HIF1A, MAX, ZNF143, CEBPG, SP7, NR2F2, TP53, PKNOX1, ZNF334, MYOD1, EGR2, BRD2, ELF3, ARID4B, AR, PAX3-FOXO1, TAF1, BHLHE40, EGLN2, EGR1, ZBTB26, HSF1, BRD4, JUND, MAZ, TBX2, AHR, FOSL2
  • Target gene symbol (double-evidenced CRMs): CRYZL1,AP000311.1,ITSN1
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 40
  • Number of somatic mutations (non-coding): 0
  • Related genes and loops
  • Related gene: ENSG00000249209, ENSG00000205758, ENSG00000205726,
  • Related loop: chr21:33625000-33650000~~chr21:33825000-33850000, chr21:33625000-33650000~~chr21:33850000-33875000, chr21:33675000-33700000~~chr21:33850000-33875000, chr21:33825000-33850000~~chr21:38075000-38100000, chr21:33850000-33875000~~chr21:33975000-34000000, chr21:33850000-33875000~~chr21:34325000-34350000, chr21:7800000-7825000~~chr21:33825000-33850000,
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