- Basic information
- CohesinDB ID: CDBP00417514
- Locus: chr21-33849970-33851666
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Data sourse: ENCSR000BTU, GSE67783, GSE86191, GSE111913, GSE206145, GSE206145-NatGen2015, ENCSR153HNT, GSE165895
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Cell type: RPE, Fibroblast, HCT-116, Ishikawa, RT-112, K-562, HSPC, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.911
- Subunit: SA1,Rad21,SA2,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 63%,
"5_TxWk": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: SMARCA2, ZNF316, ZNF263, ZSCAN5D, MYCN, SOX2, ZFX, ZNF600, WT1, ZBTB48, ZSCAN5A, FOXA1, ZNF770, ZNF485, DDX5, HOXB13, SMARCC1, ZNF384, NFIC, SMARCA4, ZNF362, RAD21, PRDM1, PBX4, ZIC2, SP140, OTX2, GATA3, PRDM9, STAT3, FOXM1, PBX3, NR3C1, NCOA3, ELF1, TRIM28, ESR1, HDAC8, ZNF334, CTCF, TCF12, T, EP300, AR, ZBTB7A, FLI1, BRD4, MAZ, TEAD4, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): ITSN1,AP000311.1,CRYZL1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 36
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000249209,
ENSG00000205758,
ENSG00000205726,
- Related loop:
chr21:33625000-33650000~~chr21:33825000-33850000,
chr21:33625000-33650000~~chr21:33850000-33875000,
chr21:33675000-33700000~~chr21:33850000-33875000,
chr21:33825000-33850000~~chr21:38075000-38100000,
chr21:33850000-33875000~~chr21:33975000-34000000,
chr21:33850000-33875000~~chr21:34325000-34350000,
chr21:7800000-7825000~~chr21:33825000-33850000,