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Basic information

CohesinDB ID: CDBP00417526

Locus: chr21-33878528-33879672

Data sourse: GSE67783, GSE111913, ENCSR153HNT, GSE86191

Cell type: K-562, RT-112, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,Rad21,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 90% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 67%, "14_ReprPCWk": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: TRIM25, PGR, SMARCA2, SOX2, NME2, XBP1, FOXA1, SUZ12, PBX2, ZNF90, ATF3, THAP1, ZBTB5, ZNF362, PRDM1, CHD7, DPF1, MITF, ZNF736, JMJD1C, TEAD1, ZNF121, TRIM28, ETV1, ESR1, OCA2, USF2, CTCF, JUN, TCF12, EP300, GATA6, RAD51, ZNF528, TEAD4, ZNF175, TFAP2C, POU2F2, BRD1, ZSCAN5D, ZNF263, MYCN, RUNX1T1, ID3, POU5F1, DUX4, ZSCAN5A, ZBTB48, STAT1, DDX5, ERG2, ASCL1, ETS1, MYC, MCM5, SMARCA4, GRHL3, STAT3, XRCC5, IKZF1, NR2F6, NR3C1, CEBPB, EZH2, FEZF1, GRHL2, PHF8, SPI1, HDAC2, RUNX1, CEBPA, ZFX, SMAD3, ZNF770, ERG3, CBX8, SMARCC1, PRDM10, CREBBP, ZNF384, RUNX2, GR, ARNT, PBX3, NR2C1, MED1, ZNF3, L3MBTL2, TBX5, USF1, REST, ZBTB7A, POU2F3, TCF3, SMC3, ELL2, STAG1, CBFA2T2, FOXA2, WT1, BCL3, YY1, RELA, TARDBP, MCM3, SP140, HIF1A, MAX, ZNF143, CBX2, PLAG1, NR2F1, KDM5B, ZBTB6, ZNF334, EGR2, T, PAX3-FOXO1, AR, TAF1, HEXIM1, HSF1, NCOR1, RNF2, BRD4, NOTCH3, ZBTB26, MAZ, AHR

Target gene symbol (double-evidenced CRMs): ITSN1,IFNGR2,CRYZL1,AP000311.1,AP000295.1,IFNAR2,SON,DONSON

Function elements

Human SNPs: .

Number of somatic mutations (coding): 12

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000249624, ENSG00000159110, ENSG00000159128, ENSG00000159140, ENSG00000159147, ENSG00000249209, ENSG00000205758, ENSG00000205726,

eachgene

Deatailed information for cohesin site CDBP00417526