- Basic information
- CohesinDB ID: CDBP00417534
- Locus: chr21-33898105-33899425
-
Data sourse: GSE67783, GSE86191, GSE111913, GSE206145-NatGen2015, ENCSR153HNT, GSE83726, GSE116344, GSE165895
-
Cell type: Fibroblast, HCT-116, RH4, RT-112, K-562, HSPC, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: SA1,Rad21,SA2,SMC1
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"5_TxWk": 79%,
"7_Enh": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: RUNX1, FOXO1, PGR, FOXA2, MYCN, ZNF660, PAF1, ZFX, ZSCAN16, ZBTB48, WT1, STAT1, FOXA1, LEO1, ERG, YY1, RELA, CREBBP, JUNB, NFIC, MYC, GATA4, RAD21, HMGB2, GABPA, ZNF189, TAL1, PBX3, FOS, SUPT5H, CDK8, ZNF736, NR3C1, CEBPB, NR2F2, LMO2, ZNF334, JUN, TCF12, RBM22, SPI1, AR, GATA2, REST, BRD4, MAZ, TEAD4, ZNF554, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): IFNAR2,IFNGR2,CRYZL1,AP000295.1,SON,ITSN1,AP000311.1,ATP5PO,DONSON
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 10
- Number of somatic mutations (non-coding): 5
- Related genes and loops
- Related gene:
ENSG00000249624,
ENSG00000159110,
ENSG00000159128,
ENSG00000159140,
ENSG00000159147,
ENSG00000249209,
ENSG00000205758,
ENSG00000205726,
ENSG00000241837,
- Related loop:
chr21:32825000-32850000~~chr21:33875000-33900000,
chr21:33199112-33200780~~chr21:33901120-33902781,
chr21:33200000-33225000~~chr21:33875000-33900000,
chr21:33200000-33225000~~chr21:33900000-33925000,
chr21:33215152-33216551~~chr21:33893787-33895793,
chr21:33225000-33250000~~chr21:33875000-33900000,
chr21:33375000-33400000~~chr21:33875000-33900000,
chr21:33478460-33481029~~chr21:33894201-33895840,
chr21:33478624-33481448~~chr21:33894294-33895564,
chr21:33541043-33543518~~chr21:33893790-33895862,
chr21:33550000-33575000~~chr21:33900000-33925000,
chr21:33575000-33600000~~chr21:33875000-33900000,
chr21:33575000-33600000~~chr21:33900000-33925000,
chr21:33587403-33589803~~chr21:33893900-33896299,
chr21:33587502-33589829~~chr21:33893790-33895862,
chr21:33600000-33625000~~chr21:33875000-33900000,
chr21:33600000-33625000~~chr21:33900000-33925000,
chr21:33604757-33606848~~chr21:33893780-33895783,
chr21:33604863-33606835~~chr21:33893985-33895886,
chr21:33605086-33606790~~chr21:33894140-33895803,
chr21:33605088-33607247~~chr21:33894294-33895564,
chr21:33605093-33606879~~chr21:33900854-33903147,
chr21:33605118-33606815~~chr21:33894143-33895729,
chr21:33605125-33606762~~chr21:33893774-33895870,
chr21:33605125-33606849~~chr21:33894235-33895673,
chr21:33605131-33606865~~chr21:33900846-33903177,
chr21:33605171-33606780~~chr21:33894237-33895772,
chr21:33608067-33609369~~chr21:33901061-33902630,
chr21:33625000-33650000~~chr21:33875000-33900000,
chr21:33640557-33644668~~chr21:33893790-33895862,
chr21:33640618-33644548~~chr21:33894152-33895934,
chr21:33640902-33645111~~chr21:33894140-33895803,
chr21:33640920-33645557~~chr21:33893756-33895853,
chr21:33640930-33643924~~chr21:33894201-33895840,
chr21:33640934-33644608~~chr21:33894206-33895853,
chr21:33640934-33645075~~chr21:33893724-33896466,
chr21:33640935-33643258~~chr21:33894239-33895642,
chr21:33640941-33644533~~chr21:33893811-33896184,
chr21:33640971-33644232~~chr21:33893800-33896251,
chr21:33650000-33675000~~chr21:33875000-33900000,
chr21:33650000-33675000~~chr21:33900000-33925000,
chr21:33675000-33700000~~chr21:33875000-33900000,
chr21:33675000-33700000~~chr21:33900000-33925000,
chr21:33700000-33725000~~chr21:33875000-33900000,
chr21:33700000-33725000~~chr21:33900000-33925000,
chr21:33750000-33775000~~chr21:33875000-33900000,
chr21:33750000-33775000~~chr21:33900000-33925000,
chr21:33775000-33800000~~chr21:33875000-33900000,
chr21:33875000-33900000~~chr21:34325000-34350000,
chr21:33900000-33925000~~chr21:34050000-34075000,
chr21:33900000-33925000~~chr21:34075000-34100000,
chr21:33900000-33925000~~chr21:34100000-34125000,
chr21:33900000-33925000~~chr21:34175000-34200000,
chr21:33900000-33925000~~chr21:34200000-34225000,
chr21:33900000-33925000~~chr21:34225000-34250000,
chr21:33900000-33925000~~chr21:34250000-34275000,
chr21:33900000-33925000~~chr21:34325000-34350000,
chr21:33900000-33925000~~chr21:34350000-34375000,
chr21:33900000-33925000~~chr21:34500000-34525000,
chr21:33900000-33925000~~chr21:34525000-34550000,
chr21:33900000-33925000~~chr21:34600000-34625000,
chr21:33900000-33925000~~chr21:34625000-34650000,
chr21:33900000-33925000~~chr21:34875000-34900000,
chr21:33900000-33925000~~chr21:36025000-36050000,
chr21:7750000-7775000~~chr21:33875000-33900000,
chr21:7750000-7775000~~chr21:33900000-33925000,
chr21:7800000-7825000~~chr21:33900000-33925000,