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Basic information

CohesinDB ID: CDBP00417537

Locus: chr21-33904131-33904969

Data sourse: GSE67783, GSE86191

Cell type: HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 90% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "4_Tx": 88%, "5_TxWk": 7%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, TRIM25, PGR, XBP1, FOXA1, RBFOX2, LEO1, PBX2, HDGF, ATF3, THAP1, CTCFL, CHD7, RUNX3, MORC2, CBFB, MXD4, ZNF189, ZSCAN4, MITF, MYOG, ZNF629, JMJD1C, TEAD1, ZNF121, TRIM28, KLF6, ETV1, BCLAF1, RBM39, SMAD5, ESR1, HDAC8, USF2, JUN, CTCF, BAF155, KLF1, MNT, RYBP, E2F6, IRF4, DEK, RAD51, E2F1, ZNF528, SMC1, TEAD4, GTF2F1, RBPJ, TFAP2C, GLIS1, JARID2, POU2F2, CHD8, BRD1, ZSCAN5D, ZNF263, MYCN, ZNF778, ID3, POU5F1, CTBP1, ZSCAN21, ZBTB17, ZBTB48, RUNX1T1, STAT1, KDM4C, SRF, ZNF134, GATAD1, SP4, TBP, ERG, MYC, HOMEZ, RAD21, GRHL3, RXRA, GABPA, STAT3, XRCC5, NKX3-1, PRDM14, IKZF1, RCOR1, HNRNPH1, NFE2, DNMT3B, NR3C1, CEBPB, ESRRA, CREB1, CCAR2, EZH2, KLF8, GRHL2, SPI1, TFE3, HDAC2, INTS13, GATA2, FLI1, MXI1, HCFC1R1, MRTFB, MYF5, ETV5, RUNX1, SMC1A, BCL6, HDAC1, SIRT6, NKX2-2, CRY1, SIN3A, CEBPA, POU4F2, ZFX, FIP1L1, SMAD3, ZNF654, NMYC, SMARCC1, CREBBP, ZBTB2, ZNF35, RUNX2, CDK6, ARNT, ZNF48, ATF2, FOXM1, MAFB, ZNF10, SUPT5H, CDK8, CHD1, MED1, CSNK2A1, TEAD3, PML, MYB, SMAD1, ZNF3, KLF9, C11orf30, L3MBTL2, RBM22, USF1, BCL11A, GSPT2, HNF4A, REST, ATF7, PHIP, TCF3, FOXP1, SMC3, STAG1, STAG2, CBFA2T2, PPARG, CBX3, ZNF316, RBBP5, CHD2, PAF1, CREM, ZNF600, E2F8, WT1, ZNF574, ZBTB33, CDK9, HOXB13, MPHOSPH8, CREB3L1, YY1, RELA, NEUROD1, SP140, TCF4, HIF1A, GATA3, ZNF519, MGA, TAL1, MAX, NRIP1, ZNF143, AGO2, GATA1, PLAG1, CEBPG, ZNF592, SP7, GFI1B, NCOA3, KDM5B, TP53, ZBTB6, ZNF334, AR, ZNF324, EGLN2, ZBTB26, MYNN, BRD4, JUND, ILF3, MAZ, ZNF24, AHR

Target gene symbol (double-evidenced CRMs): AP000311.1,MRPS6,ATP5PO,RUNX1,SLC5A3,ITSN1,SON,AP000295.1,IFNAR2,SMIM11A,RCAN1,CRYZL1,DONSON

Function elements

Human SNPs: .

Number of somatic mutations (coding): 2

Number of somatic mutations (non-coding): 1

Related genes and loops

Related gene: ENSG00000249624, ENSG00000159110, ENSG00000159140, ENSG00000159147, ENSG00000249209, ENSG00000205758, ENSG00000205726, ENSG00000241837, ENSG00000243927, ENSG00000198743, ENSG00000205670, ENSG00000159200, ENSG00000159216,

eachgene

Deatailed information for cohesin site CDBP00417537