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Basic information

CohesinDB ID: CDBP00417550

Locus: chr21-33944484-33945768

Data sourse: GSE67783, ENCSR153HNT, GSE98367

Cell type: K-562, HSPC, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 90% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 42%, "5_TxWk": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: POU2F2, CHD8, NANOG, FOXA2, POU5F1, CBX3, SOX2, ZFX, MTA2, DUX4, FOXA1, ERG, KDM1A, NEUROD1, CHD7, GRHL3, HIF1A, ZFP36, OTX2, BATF, STAT3, TP63, ZNF143, NR3C1, CEBPB, STAT5B, TRIM28, SNAI2, ESR1, PKNOX1, CTCF, USF1, BCL11A, GATA6, DPF2, TRIM24, NCOR1, SCRT1, BRD4, BCOR, CLOCK, AFF1, RELB, ZNF92

Target gene symbol (double-evidenced CRMs): SLC5A3,RCAN1,MRPS6,SMIM11A

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 5

Related genes and loops

Related gene: ENSG00000243927, ENSG00000198743, ENSG00000205670, ENSG00000159200,

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Deatailed information for cohesin site CDBP00417550