- Basic information
- CohesinDB ID: CDBP00417554
- Locus: chr21-33956181-33956281
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Data sourse: GSE120943, GSE98367
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Cell type: Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 83%,
"5_TxWk": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: HDGF, TARDBP, ZBTB2, JUNB, SMC1A, MYC, ZNF263, TOP2A, ATF7, ZMYM3, MTA2, SKIL, PKNOX1, RELB, BATF, ZSCAN4, TRIM22, STAT2, SPI1
- Target gene symbol (double-evidenced CRMs): RCAN1,SMIM11A,MRPS6,SLC5A3,RUNX1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000243927,
ENSG00000198743,
ENSG00000205670,
ENSG00000159200,
ENSG00000159216,
- Related loop:
chr21:33950000-33975000~~chr21:34050000-34075000,
chr21:33950000-33975000~~chr21:34200000-34225000,
chr21:33950000-33975000~~chr21:34325000-34350000,
chr21:33950000-33975000~~chr21:34350000-34375000,
chr21:33950000-33975000~~chr21:34500000-34525000,
chr21:33950000-33975000~~chr21:34525000-34550000,
chr21:33950000-33975000~~chr21:34600000-34625000,
chr21:33950000-33975000~~chr21:34625000-34650000,
chr21:33950000-33975000~~chr21:34800000-34825000,