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Basic information

CohesinDB ID: CDBP00417556

Locus: chr21-33963087-33963651

Data sourse: GSE206145-NatGen2015, GSE67783, ENCSR153HNT, GSE86191

Cell type: K-562, Fibroblast, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 90% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 67%, "5_TxWk": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, GLIS1, FOXO1, NCOA2, POU2F2, CHD8, PPARG, ZSCAN5D, MYCN, TBL1X, CBFA2T2, ID3, ZFX, XBP1, ZBTB48, WT1, ZNF823, PBX2, YY1, RELA, ZNF384, ATF3, MYC, CTCFL, RAD21, ARNT, BACH1, GRHL3, ATF4, SMAD4, ZNF189, STAT3, MAX, NR2C1, IKZF1, TERF2, ZNF736, CEBPB, GFI1B, TRIM28, SCRT2, ZNF680, ZNF3, ESR1, HDAC8, CTCF, ELF3, TCF12, SPI1, NR4A1, AR, IRF1, TAF1, PTRF, ZNF644, EGLN2, CREB3, NOTCH3, SCRT1, DDX20, BRD4, SMC3, MEF2D, ILK, STAG1, PTTG1

Target gene symbol (double-evidenced CRMs): SLC5A3,RCAN1,RUNX1,MRPS6,SMIM11A

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 4

Related genes and loops

Related gene: ENSG00000243927, ENSG00000198743, ENSG00000205670, ENSG00000159200, ENSG00000159216,

eachgene

Deatailed information for cohesin site CDBP00417556