- Basic information
- CohesinDB ID: CDBP00417565
- Locus: chr21-33986585-33988056
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Data sourse: GSE67783, GSE86191, GSE206145, GSE206145-NatGen2015, ENCSR153HNT
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Cell type: RPE, Fibroblast, HCT-116, K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 58%,
"14_ReprPCWk": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, ZNF195, HMG20A, ZNF621, XBP1, FOXA1, SUZ12, RXRB, ZNF28, ZFHX2, HDGF, TSC22D4, ZNF274, ATF3, NFIC, BMI1, ZBTB5, RUNX3, ZNF444, CBFB, SMARCE1, PAX5, TP63, CDC5L, JMJD1C, ELF1, TRIM28, BCLAF1, TEAD1, KLF6, ZNF217, ESR1, OCA2, USF2, ZIK1, CTCF, TCF12, E4F1, ZBTB20, ZNF157, MNT, DPF2, E2F6, IRF4, TRIM24, GLI4, ZNF407, ZNF211, E2F4, RAD51, ZNF410, ZNF512B, ZNF776, ZNF280A, FOXA3, GATAD2A, EHMT2, TFAP2C, EED, RBPJ, YBX1, GLIS1, POU2F2, CHD8, NANOG, ZSCAN5D, ZNF263, MYCN, TOP2A, POU5F1, ZNF239, CTBP1, MTA2, RUNX1T1, ZBTB48, ZSCAN5A, ZSCAN21, BRD1, ID3, SRF, ZNF488, DDX5, NBN, ERG2, PHB2, GATAD1, TBP, ZNF300, ERG, ZNF114, MIER1, ZNF341, OGG1, MYC, ETS1, SMARCA4, RFX1, ZKSCAN2, RAD21, GRHL3, STAT3, XRCC5, ZNF614, ZNF398, IKZF1, MIER3, ZNF639, ARNTL, CEBPB, SRSF3, HNRNPL, CREB1, YBX3, EZH2, ARHGAP35, FEZF1, GABPB1, SPI1, HES1, TFE3, IRF1, HDAC2, SSRP1, ZNF182, ZNF644, GATAD2B, MXD3, DRAP1, ZNF785, ZGPAT, SMARCA5, RELB, NFYB, PTBP1, SALL2, CC2D1A, RUNX1, ETV5, THAP11, SMC1A, HDAC1, ZNF707, CRY1, SOX13, ZFX, ZNF747, TET2, ZNF473, ERG3, NFXL1, TRIM22, ZNF18, PRDM10, ZBTB2, CREBBP, NOTCH1, ZNF133, ZNF169, RARA, RUNX2, NFYC, ZNF384, OSR2, ZNF184, ARNT, BACH1, ZBTB10, ATF2, PRDM9, SMAD4, ZNF48, ETV6, FOXM1, PBX3, SUPT5H, HMGXB4, SNRNP70, MED1, TEAD3, ZEB1, TERF1, ZNF670, ZNF680, KDM6B, KLF9, NCOA1, L3MBTL2, USF1, NIPBL, SP1, BCL11A, NR4A1, GSPT2, PHF20, ARID2, IKZF5, ATF7, ASH2L, PHIP, TCF3, BCOR, SALL1, AATF, SMC3, STAG1, MLLT1, NFATC3, TRP47, NCOA4, MEF2B, ZNF316, FOXA2, TBL1X, EBF1, CREM, ZNF207, MTA3, ZNF600, MIER2, CHD2, WT1, ZNF662, MEF2C, ZBTB33, ZNF580, BCL3, ZKSCAN1, YY1, RELA, TARDBP, JUNB, ZNF148, ZNF266, ZNF521, SP140, ZIC2, SKIL, HIF1A, ZNF311, BATF, MGA, TAL1, MAX, MAF1, GATA1, ZNF143, ZSCAN26, PLAG1, ZFP69B, ZNF592, ZNF544, NR2F1, ZNF791, KDM5B, TP53, ZNF687, PKNOX1, IRF5, ZNF140, EGR2, BRD2, KAT8, TBX21, BHLHE40, AR, ZBTB40, EGR1, RB1, HSF1, ZBTB26, IKZF2, BRD4, NCOR1, RNF2, CLOCK, MAZ, ZSCAN23, MEF2D, ZNF24, ADNP, AHR
- Target gene symbol (double-evidenced CRMs): RCAN1,ITSN1,AP000311.1,MRPS6
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 7
- Related genes and loops