- Basic information
- CohesinDB ID: CDBP00417571
- Locus: chr21-33998277-33999545
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Data sourse: GSE67783, ENCSR879KXD, GSE206145, ENCSR153HNT, GSE68388, GSE116344
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Cell type: RPE, RH4, K-562, HSPC, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: Mau2,SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 73%,
"7_Enh": 13%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, NFIA, FOXA2, LDB1, MYCN, TOP2A, ZFX, CTBP1, WT1, CDK9, HOXB13, RUNX2, MYC, NFIC, GRHL3, ARNT, ZFP36, OTX2, GATA3, GABPA, TAL1, GATA1, NFE2, NR3C1, ELF1, STAT5B, TFAP2C, TP53, ZBTB6, ELF3, TCF12, CTCF, SPI1, BCL11A, TBX21, LMO1, ZNF257, GATA2, NOTCH3, BRD4, TEAD4, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): RCAN1,ITSN1,MRPS6,AP000311.1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 3
- Related genes and loops