- Basic information
- CohesinDB ID: CDBP00417577
- Locus: chr21-34011115-34012806
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Data sourse: GSE98367, GSE111913, GSE206145, GSE206145-NatGen2015, ENCSR153HNT, GSE50893
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Cell type: RPE, Fibroblast, RT-112, K-562, GM18951, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: NIPBL,SA1,SA2,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"9_Het": 51%,
"15_Quies": 44%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: POU2F2, SMC1A, CBX5, HDAC1, MTA3, MEIS2, CTBP1, XBP1, ZFX, SMAD3, ZBTB48, ZNF534, BAHD1, PBX2, ERG, RELA, ZNF384, ZNF169, ZNF274, MYC, GRHL3, STAT3, TAL1, ZNF143, VDR, NR2F2, TRIM28, NR2F1, TP53, ESR1, SETDB1, BCL11A, NIPBL, ZNF324, BRD4
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 19
- Related genes and loops