- Basic information
- CohesinDB ID: CDBP00417587
- Locus: chr21-34031836-34032471
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Data sourse: GSE72082, ENCSR054FKH, ENCSR153HNT, GSE131606, GSE50893
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Cell type: GM12892, GM2630, SNYDER, Hep-G2, GM2610, GM19240, GM12878, GM12891, GM2588, GM12890, GM19238, GM2255, K-562, GM19239, GM18486, DKO
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 5% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.822
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 60%,
"5_TxWk": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, PGR, HMG20A, NME2, FOXA1, RXRB, UBTF, PAX5, CDX2, KLF5, KLF6, ESR1, CTCF, TCF12, BAF155, DPF2, IRF4, CREB3, E2F4, E2F1, FOXA3, GATAD2A, RBPJ, POU5F1, BRD3, TOP2A, DUX4, GATAD1, SAP130, ERG, MYC, HOMEZ, PROX1, STAT3, XRCC5, NKX3-1, MIER3, NR2F6, VDR, NR3C1, ESRRA, CREB1, EZH2, SPI1, IRF1, GATA2, ZNF644, HCFC1, NR2C2, ATF1, ETV5, THAP11, SOX13, POU4F2, RARA, IRF2, GR, ARNT, ZNF48, SMAD4, NR2C1, MED1, ZEB1, DIDO1, TEAD3, PHF20, ASH2L, MLLT1, CBX3, CREM, GTF2B, CDK9, ZNF580, RELA, TARDBP, JUNB, TCF4, BATF, MAX, MTA1, KLF4, ZNF592, NR2F2, ZNF512, NR2F1, TP53, BRD2, ELF3, KAT8, NFKBIZ, AR, ZBTB40, RXR, ZBTB26, RNF2, BRD4, JUND, AHR
- Target gene symbol (double-evidenced CRMs): RCAN1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops