- Basic information
- CohesinDB ID: CDBP00417588
- Locus: chr21-34033800-34034350
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Data sourse: ENCSR000EDW, ENCSR153HNT, GSE86191
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Cell type: K-562, HCT-116, Hep-G2
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SMC3,Rad21,SA1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 64%,
"5_TxWk": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, HMG20A, XBP1, FOXA1, HLF, RXRB, ZFHX2, TFAP4, NFIC, CHD7, TP63, TEAD1, SNAI2, ESR1, TP73, CTCF, TCF12, JUN, EP300, PAX8, E2F1, ZNF528, TEAD4, FOXA3, GATAD2A, POU2F2, CHD8, POU5F1, MYCN, TOP2A, ZSCAN5A, SAP130, ERG2, MYC, SMARCA4, RAD21, STAT3, XRCC5, ZNF614, IKZF1, RCOR1, NR3C1, CEBPB, ZNF750, CREB1, EZH2, GRHL2, GATA2, ZNF644, FLI1, MRTFB, NFIL3, ATF1, THAP11, BCL6, SMC1A, CEBPA, SOX13, ZFX, ZNF534, SIN3A, SMAD3, ERG3, RARA, ZNF384, CREBBP, GATA4, OSR2, GR, ARNT, ATF2, ZEB2, SMAD4, NR2C1, FOS, TEAD3, ZNF331, USF1, GSPT2, REST, ZBTB7A, CTBP2, SMC3, STAG1, SKI, FOXA2, ZNF207, WT1, ZNF662, KDM1A, CREB3L1, YY1, RELA, JUNB, ZIC2, HIF1A, GATA3, MAX, GATA1, CEBPG, KLF4, NR2F1, TP53, ZNF334, NFKB1, MYOD1, EGR2, ELF3, BRD2, KAT8, AR, PAX3-FOXO1, ZBTB26, NOTCH3, BRD4
- Target gene symbol (double-evidenced CRMs): RCAN1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops