- Basic information
- CohesinDB ID: CDBP00417591
- Locus: chr21-34039740-34040505
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Data sourse: ENCSR000BLD, ENCSR167MTG, ENCSR000EEG, GSE143937, ENCSR230ZWH, ENCSR000BKV, ENCSR000FAD, GSE72082, GSE126634, GSE110061, ENCSR879KXD, ENCSR000BLS, GSE105028, ENCSR000ECE, ENCSR000BMY, GSE25021, ENCSR000EDW, ENCSR917QNE
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Cell type: MCF-7, H1-hESC, HCT-116, Hep-G2, GM12878, K-562, Liver, HAP1, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.900
- Subunit: SMC3,Rad21,SA1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 72%,
"14_ReprPCWk": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: POU5F1, TOP2A, FOXA1, ZBTB33, SAP130, CBX8, HNF4G, YY1, RELA, BMI1, MYC, RAD21, PRDM1, ZFP36, RUNX3, HIF1A, RXRA, BATF, SMAD4, GABPA, MAX, XRCC5, IKZF1, ARNTL, ZEB1, NR2F2, ELF1, NR2F1, EZH2, TP53, NFKB1, CTCF, ELF3, SP1, SPI1, HNF4A, GATA6, DPF2, REST, GATAD2B, ZBTB26, RNF2, JUND, SCRT1, SMARCA5, ZNF677, SMC3, STAG1, AHR, EED
- Target gene symbol (double-evidenced CRMs): RCAN1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 1
- Related genes and loops