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Basic information

CohesinDB ID: CDBP00417593

Locus: chr21-34045087-34045566

Data sourse: GSE67783, ENCSR153HNT, ENCSR879KXD

Cell type: K-562, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 91% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 87%, "14_ReprPCWk": 11%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: XBP1, FOXA1, ZFHX2, HDGF, ATF3, NFIC, BMI1, RUNX3, PRDM1, CBFB, ELF1, TRIM28, BCLAF1, LMO2, ZNF217, TP73, JUN, PAX8, DPF2, IRF4, RAD51, RBPJ, EED, TOP2A, MTA2, ZNF205, NBN, ARID3A, BAHD1, ERG, OGG1, ZNF597, MYC, SMARCA4, RAD21, FOXK2, BATF3, GABPA, STAT3, IKZF1, TERF2, ARNTL, CREB1, EZH2, SPI1, ZNF664, ZNF182, SMARCA5, RELB, SMC1A, BCL6, CBX8, TRIM22, ZNF18, MEF2A, ZBTB2, ZNF384, ARNT, ATF2, PRDM9, FOXM1, ETV6, SP2, ZNF10, FOS, MED1, PML, SCRT2, ZMYM3, NIPBL, BCL11A, SP1, RBM25, ATF7, ASH2L, PHIP, MLLT1, NFATC3, MEF2B, ZNF207, CREM, NFATC1, E2F8, ZBED1, GTF2B, ZNF662, ZBTB33, TCF7, MEF2C, CDK9, RELA, TARDBP, JUNB, SKIL, BATF, ZNF143, ZFP69B, TCF7L2, NR2F1, ZNF687, PKNOX1, TBX21, BHLHE40, ZBTB40, RB1, RNF2, NOTCH3, JUND, BRD4, SCRT1, IKZF2

Target gene symbol (double-evidenced CRMs): RCAN1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 6

Related genes and loops

Related gene: ENSG00000159200,

eachgene

Deatailed information for cohesin site CDBP00417593