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Basic information

CohesinDB ID: CDBP00417594

Locus: chr21-34046599-34047862

Data sourse: GSE38395, GSE93080, ENCSR000EAC, ENCSR000DZP, GSE67783, GSE86191, GSE111913, GSE62063, ENCSR000BMY, ENCSR153HNT, GSE131606, GSE50893

Cell type: GM12892, GM2630, HCT-116, SNYDER, GM19240, GM12878, GM12891, GM2588, hLCL, RT-112, GM2255, K-562, HSPC, Ramos

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 5% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.844

Subunit: NIPBL,SA1,Rad21,SMC1,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 91% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 81%, "14_ReprPCWk": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RELA, NR3C1, MAFG, E2F6, MYC, POU5F1, ZNF280A, TOP2A, GATA4, ZNF777, RNF2, MAFF, C11orf30, SETDB1, MGA, CBX8, MAX, PAX5, MAFK, ZNF316

Target gene symbol (double-evidenced CRMs): RCAN1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 12

Related genes and loops

Related gene: ENSG00000159200,

eachgene

Deatailed information for cohesin site CDBP00417594