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Basic information

CohesinDB ID: CDBP00417597

Locus: chr21-34050980-34051129

Data sourse: GSE120943, GSE98367

Cell type: Monocytes, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 91% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 92%, "14_ReprPCWk": 7%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: POU2F2, MAFG, FOXA2, POU5F1, NME2, ZFX, ZSCAN16, GTF2B, DUX4, FOXA1, ZBTB33, CDK9, PRDM10, RELA, AHR, RUNX2, MYC, GRHL3, TCF4, GABPA, MAX, ZSCAN4, ZNF143, MED1, KDM5B, EZH2, TP53, ESR1, OCA2, C11orf30, L3MBTL2, SPI1, AR, IRF1, IRF4, ZBTB42, RNF2, BRD4, ZNF528, ZNF24, ZNF316

Target gene symbol (double-evidenced CRMs): SMIM11A,GART,AP000311.1,SON,RCAN1,ITSN1,ATP5PO

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000159131, ENSG00000159140, ENSG00000249209, ENSG00000205726, ENSG00000241837, ENSG00000205670, ENSG00000159200,

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Deatailed information for cohesin site CDBP00417597