- Basic information
- CohesinDB ID: CDBP00417599
- Locus: chr21-34052673-34053743
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Data sourse: GSE67783, ENCSR153HNT, GSE86191
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Cell type: K-562, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 91%,
"14_ReprPCWk": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: POU2F2, MAFG, FOXA2, POU5F1, NME2, ZFX, ZSCAN16, GTF2B, DUX4, FOXA1, ZBTB33, CDK9, PRDM10, RELA, AHR, RUNX2, MYC, GRHL3, TCF4, GABPA, MAX, ZSCAN4, ZNF143, MED1, KDM5B, EZH2, TP53, ESR1, OCA2, C11orf30, L3MBTL2, SPI1, AR, IRF1, IRF4, ZBTB42, RNF2, BRD4, ZNF528, ZNF24, ZNF316
- Target gene symbol (double-evidenced CRMs): GART,ITSN1,SON,ATP5PO,SMIM11A,AP000311.1,RCAN1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 6
- Related genes and loops
- Related gene:
ENSG00000159131,
ENSG00000159140,
ENSG00000249209,
ENSG00000205726,
ENSG00000241837,
ENSG00000205670,
ENSG00000159200,
- Related loop:
chr21:33525000-33550000~~chr21:34050000-34075000,
chr21:33675000-33700000~~chr21:34050000-34075000,
chr21:33900000-33925000~~chr21:34050000-34075000,
chr21:33925000-33950000~~chr21:34050000-34075000,
chr21:33950000-33975000~~chr21:34050000-34075000,
chr21:34025000-34050000~~chr21:34500000-34525000,
chr21:34050000-34075000~~chr21:34200000-34225000,
chr21:34050000-34075000~~chr21:34250000-34275000,
chr21:34050000-34075000~~chr21:34325000-34350000,
chr21:34050000-34075000~~chr21:34350000-34375000,
chr21:34050000-34075000~~chr21:34500000-34525000,
chr21:34050000-34075000~~chr21:34600000-34625000,