- Basic information
- CohesinDB ID: CDBP00417602
- Locus: chr21-34057409-34058775
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Data sourse: GSE67783, GSE86191, GSE98367, GSE206145, ENCSR153HNT
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Cell type: RPE, HCT-116, K-562, HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 83%,
"14_ReprPCWk": 11%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: AR, KLF4, PGR, GATA2, RUNX2, MYCN, ZFX, WT1, GATA3, ZNF766, DDX5, ELF3, GATA1
- Target gene symbol (double-evidenced CRMs): ITSN1,RCAN1,SON,SMIM11A,AP000311.1,ATP5PO,GART
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops
- Related gene:
ENSG00000159131,
ENSG00000159140,
ENSG00000249209,
ENSG00000205726,
ENSG00000241837,
ENSG00000205670,
ENSG00000159200,
- Related loop:
chr21:33525000-33550000~~chr21:34050000-34075000,
chr21:33675000-33700000~~chr21:34050000-34075000,
chr21:33900000-33925000~~chr21:34050000-34075000,
chr21:33925000-33950000~~chr21:34050000-34075000,
chr21:33950000-33975000~~chr21:34050000-34075000,
chr21:34050000-34075000~~chr21:34200000-34225000,
chr21:34050000-34075000~~chr21:34250000-34275000,
chr21:34050000-34075000~~chr21:34325000-34350000,
chr21:34050000-34075000~~chr21:34350000-34375000,
chr21:34050000-34075000~~chr21:34500000-34525000,
chr21:34050000-34075000~~chr21:34600000-34625000,