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Basic information

CohesinDB ID: CDBP00417605

Locus: chr21-34065023-34065565

Data sourse: GSE98367, GSE138405, GSE206145-NatGen2015, ENCSR153HNT, GSE103477, GSE126990

Cell type: MDM, Hela-Kyoto, Fibroblast, K-562, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: SA1,Rad21,SMC1,SA2,Mau2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 91% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 65%, "14_ReprPCWk": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, NFIA, CHD8, BRD1, FOXA2, SMARCA2, ZFX, CTBP1, MEIS2, ZBTB17, WT1, ZSCAN5A, PBX2, MLL4, SMARCC1, RELA, ATF3, NFIC, RUNX2, SMARCA4, RAD21, NRF1, GRHL3, RXRA, OTX2, XRCC5, IKZF1, RCOR1, MITF, MED1, KLF4, CEBPB, NR3C1, KLF5, GFI1B, NR2F2, TEAD1, SCRT2, EZH2, TP53, SPI1, AR, YAP1, GATA2, SIX2, FLI1, BRD4, TEAD4

Target gene symbol (double-evidenced CRMs): RCAN1,SMIM11A,AP000311.1,ATP5PO,GART,SON,ITSN1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 9

Related genes and loops

Related gene: ENSG00000159131, ENSG00000159140, ENSG00000249209, ENSG00000205726, ENSG00000241837, ENSG00000205670, ENSG00000159200,

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Deatailed information for cohesin site CDBP00417605