Deatailed information for cohesin site CDBP00417616

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  • Basic information
  • CohesinDB ID: CDBP00417616
  • Locus: chr21-34086684-34087838
  • Data sourse: GSE206145-GSE177045, GSE72082, GSE86191, GSE98367, GSE76893, ENCSR879KXD, ENCSR153HNT, ENCSR703TNG, GSE25021
  • Cell type: K-562, MCF-7, HCT-116, Macrophage
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 4% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.956
  • Subunit: Mau2,SA1,Rad21,SMC1
  • CTCF binding site: non-CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True
  • Compartment: 91% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "5_TxWk": 57%, "7_Enh": 28%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: PGR, MEIS2, NME2, XBP1, FOXA1, RBFOX2, PBX2, HDGF, MEN1, ATF3, SMARCE1, PAX5, ZSCAN4, TEAD1, TRIM28, ZNF573, NFE2L2, LMO2, ESR1, ZNF217, CTCF, JUN, BAF155, EP300, DPF2, PAX8, SOX6, E2F1, TEAD4, ZNF175, TFAP2C, POU2F2, CHD8, BRD1, POU5F1, ZNF263, ID3, CTBP1, DUX4, NBN, TBP, ERG, MYC, SMARCA4, RFX1, ARID1B, RAD21, GRHL3, RCOR1, NFE2, ARNTL, NR3C1, CEBPB, STAT5B, KMT2A, CREB1, TBL1XR1, GRHL2, FEZF1, TRPS1, HES1, SPI1, HDAC2, GATA2, SSRP1, GATAD2B, SMARCA5, ZIM3, NCOA2, RUNX1, MAFG, CBX1, HDAC1, SIN3A, ZFX, POU4F2, ZNF534, CREBBP, ZXDC, RUNX2, ARNT, HMBOX1, ZEB2, CBFA2T3, SUPT5H, GMEB1, MYB, PIAS1, C11orf30, L3MBTL2, TBX5, RBM22, MAFK, NIPBL, BCL11A, ZBTB7A, ATF7, CTBP2, MBD2, FOXP1, ZNF337, MLLT1, STAG1, PPARG, ZNF316, MTA3, CREM, PAF1, NFATC1, ZNF600, MAFF, ZNF30, HOXB13, ZKSCAN1, ZNF318, KDM1A, RELA, TARDBP, HIF1A, GATA3, MGA, TAL1, MAX, NRIP1, GATA1, MTA1, ZNF143, AGO2, TLE3, NCOA3, NR2F2, GFI1B, TCF7L2, TP53, MYOD1, TBX21, AR, EGLN2, ZBTB42, RNF2, NCOR1, JUND, ILF3, BRD4, ZNF24, AHR
  • Target gene symbol (double-evidenced CRMs): AP000311.1,ATP5PO,SLC5A3,MRPS6,ITSN1
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 6
  • Number of somatic mutations (non-coding): 0
  • Related genes and loops
  • Related gene: ENSG00000249209, ENSG00000205726, ENSG00000241837, ENSG00000243927, ENSG00000198743,
  • Related loop: chr21:33900000-33925000~~chr21:34075000-34100000, chr21:33925000-33950000~~chr21:34075000-34100000, chr21:33967731-33970173~~chr21:34092084-34093399, chr21:34075000-34100000~~chr21:34175000-34200000, chr21:34075000-34100000~~chr21:34325000-34350000,
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