- Basic information
- CohesinDB ID: CDBP00417618
- Locus: chr21-34089020-34089310
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Data sourse: GSE67783, ENCSR153HNT
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Cell type: K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 81%,
"7_Enh": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, PGR, ZSCAN5C, ZNF660, SOX2, MEIS2, PATZ1, FOXA1, RBFOX2, PBX2, ZFHX2, CTCFL, IKZF3, ZNF189, MECOM, SMARCE1, MZF1, ZNF467, ZNF629, ELF1, BCLAF1, KLF6, ESR1, ZNF561, CTCF, JUN, BAF155, ZNF260, SOX5, PAX8, SOX6, SMC1, ZNF92, FOXA3, PDX1, TFAP2C, CHD8, POU5F1, ZSCAN21, ZBTB17, ZBTB48, ZSCAN5A, DUX4, NONO, SRF, ERG2, TBP, ERG, ETS1, MYC, RAD21, NKX2-1, NKX3-1, RCOR1, NFE2, ZNF639, ZNF750, KMT2A, KLF8, SPI1, IRF1, GATA2, FLI1, RUNX1, SMC1A, NKX2-2, SOX13, ZFX, SIN3A, ZNF770, ERG3, TRIM22, PRDM10, ZBTB2, ZNF384, NOTCH1, ZNF35, RUNX2, GATA4, OSR2, ZNF184, ZEB2, FOS, CDK8, ZXDB, MYB, SCRT2, ZMYM3, EVI1, RBM22, BCL11A, HNF4A, REST, ZNF479, RBM25, PHIP, FOXP1, PRDM6, SMC3, ZNF34, STAG1, FOXA2, NFATC1, PAF1, ZNF600, ZNF692, ZSCAN16, WT1, MEF2C, CDK9, HOXB13, KDM1A, RELA, NEUROD1, HIF1A, OTX2, TAL1, MAX, SPIB, GATA1, AGO2, ZNF143, KLF4, SP7, GFI1B, KDM5B, TP53, PKNOX1, EGR2, BRD2, ELF3, BHLHE40, AR, MYNN, SCRT1, BRD4, MAZ
- Target gene symbol (double-evidenced CRMs): SLC5A3,ITSN1,ATP5PO,AP000311.1,MRPS6
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000249209,
ENSG00000205726,
ENSG00000241837,
ENSG00000243927,
ENSG00000198743,
- Related loop:
chr21:33900000-33925000~~chr21:34075000-34100000,
chr21:33925000-33950000~~chr21:34075000-34100000,
chr21:33967731-33970173~~chr21:34092084-34093399,
chr21:34075000-34100000~~chr21:34175000-34200000,
chr21:34075000-34100000~~chr21:34325000-34350000,