- Basic information
- CohesinDB ID: CDBP00417620
- Locus: chr21-34094869-34095426
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Data sourse: ENCSR230ZWH, ENCSR917QNE
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Cell type: Liver
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"4_Tx": 49%,
"5_TxWk": 44%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: POU2F2, CHD8, PGR, FOXA2, ZSCAN5D, PAF1, ZFX, NFATC1, FIP1L1, SIN3A, DUX4, ZSCAN5A, XBP1, FOXA1, ZNF770, ZBTB33, RBFOX2, CDK9, LEO1, HNF4G, ZNF300, YY1, RELA, NEUROD1, ATF3, MYC, ONECUT1, SMARCA4, GATA4, RAD21, HIF1A, RXRA, SMC3, GABPA, TAL1, MAX, XRCC5, SUPT5H, IKZF1, AGO2, DNMT3B, KLF4, NCOA3, NR2F2, TRIM28, RBM39, SCRT2, LMO2, TP53, OCA2, ZIM3, ZNF334, ZNF565, CTCF, RBM22, JUN, SP1, EP300, SPI1, MNT, HNF4A, IRF1, BHLHE40, AR, REST, SSRP1, POU2F3, FLI1, NOTCH3, BRD4, JUND, IKZF2, FOXP1, RELB, NCOA2
- Target gene symbol (double-evidenced CRMs): SLC5A3,MRPS6,ITSN1,ATP5PO,AP000311.1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 90
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000249209,
ENSG00000205726,
ENSG00000241837,
ENSG00000243927,
ENSG00000198743,
- Related loop:
chr21:33700000-33725000~~chr21:34100000-34125000,
chr21:33775000-33800000~~chr21:34100000-34125000,
chr21:33900000-33925000~~chr21:34075000-34100000,
chr21:33900000-33925000~~chr21:34100000-34125000,
chr21:33925000-33950000~~chr21:34075000-34100000,
chr21:33967731-33970173~~chr21:34092084-34093399,
chr21:34075000-34100000~~chr21:34175000-34200000,
chr21:34075000-34100000~~chr21:34325000-34350000,
chr21:34100000-34125000~~chr21:34200000-34225000,
chr21:34100000-34125000~~chr21:34325000-34350000,
chr21:34100000-34125000~~chr21:34350000-34375000,
chr21:34100000-34125000~~chr21:34600000-34625000,