- Basic information
- CohesinDB ID: CDBP00417624
- Locus: chr21-34108598-34109091
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Data sourse: ENCSR000BLD, ENCSR000EAC, GSE143937, ENCSR230ZWH, ENCSR000BKV, GSE72082, ENCSR879KXD, ENCSR000BLS, ENCSR000ECE, ENCSR153HNT, GSE97394, GSE50893
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Cell type: H1-hESC, Hep-G2, GM12878, GM2588, K-562, Liver, HUES64
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 72%,
"15_Quies": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, GLIS1, PGR, ZNF316, FOXA2, NKX2-2, RUNX1T1, SOX2, PAF1, ZFX, XBP1, GTF2B, DUX4, FOXA1, ZBTB33, RELA, ZNF384, OGG1, NEUROD1, GATA4, SMARCA4, RAD21, HIF1A, ATF4, OTX2, GATA3, TAL1, MAX, PBX3, NKX3-1, SUPT5H, AGO2, ZNF449, GATA1, MITF, MED1, NR3C1, CEBPB, TRIM28, SCRT2, TFAP2C, MLLT1, ESR1, TP53, KLF9, C11orf30, ZNF22, CTCF, RBM22, MAFK, SPI1, BCL11A, BAF155, AR, GATA2, REST, NOTCH3, BRD4, SCRT1, FOXP1, ZNF440, PDX1, AHR
- Target gene symbol (double-evidenced CRMs): RCAN1,ITSN1,ATP5PO,SMIM11A,SLC5A3,MRPS6,AP000311.1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 2
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000249209,
ENSG00000205726,
ENSG00000241837,
ENSG00000243927,
ENSG00000198743,
ENSG00000205670,
ENSG00000159200,
- Related loop:
chr21:33700000-33725000~~chr21:34100000-34125000,
chr21:33775000-33800000~~chr21:34100000-34125000,
chr21:33900000-33925000~~chr21:34100000-34125000,
chr21:33922677-33925654~~chr21:34108278-34109481,
chr21:34100000-34125000~~chr21:34200000-34225000,
chr21:34100000-34125000~~chr21:34325000-34350000,
chr21:34100000-34125000~~chr21:34350000-34375000,
chr21:34100000-34125000~~chr21:34600000-34625000,