Deatailed information for cohesin site CDBP00417625

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  • Basic information
  • CohesinDB ID: CDBP00417625
  • Locus: chr21-34110152-34111183
  • Data sourse: ENCSR000FAD, GSE98367, GSE111913, ENCSR879KXD, GSE206145, ENCSR153HNT, GSE73207
  • Cell type: RPE, TF-1, RT-112, K-562, Macrophage
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 2% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.944
  • Subunit: NIPBL,SA1,Rad21,SMC1,SA2,SMC3
  • CTCF binding site: non-CTCF CTCF motif: False
  • Genomic location: TES
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True
  • Compartment: 91% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "5_TxWk": 64%, "15_Quies": 15%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOSL1, HMGN3, MEIS2, SOX2, XBP1, FOXA1, SUZ12, LEO1, PBX2, HNRNPK, HDGF, ATF3, NFIC, ATF4, CBFB, SMARCE1, HDAC3, RLF, TRIM28, E2F5, NFE2L2, HDAC8, ZFP91, JUN, TCF12, CTCF, EP300, E4F1, MNT, GATA6, PYGO2, PAX8, DPF2, E2F6, TRIM24, CREB3, SOX6, DDX20, TEAD4, ZNF175, GTF2F1, GATAD2A, EHMT2, ZSCAN5D, POU5F1, ID3, CTBP1, MTA2, NONO, NBN, ARID3A, PHB2, SMARCC2, ONECUT1, MYC, SMARCA4, RFX1, ARID1B, FOXK2, GABPA, IKZF1, LEF1, RCOR1, DACH1, NR2F6, NFE2, ZNF639, NR3C1, CEBPB, ESRRA, NFRKB, KMT2A, CREB1, TBL1XR1, HDAC2, GATA2, SSRP1, ZNF644, GATAD2B, MXI1, NR2C2, ATF1, CC2D1A, RUNX1, SMC1A, HDAC1, LDB1, CEBPA, SOX13, ZFX, ZMIZ1, SMARCC1, PRDM10, ZNF384, RUNX2, GATA4, ZNF184, ARNT, TFDP1, ATF2, ZEB2, HMBOX1, CBFA2T3, FOXM1, FOXJ2, SMARCB1, SUPT5H, FOS, MED1, ZNF584, GMEB1, PML, CEBPD, SMAD1, NCOA1, L3MBTL2, STAT5A, KLF16, RBM22, BCL11A, NR4A1, PHF20, REST, ZBTB7A, CCNT2, ATF7, BCOR, MBD2, NFATC3, CBFA2T2, FOXA2, MTA3, CREM, CBX3, PAF1, RBBP5, ZBED1, MEF2C, MPHOSPH8, ZNF589, KDM1A, RELA, YY1, TARDBP, JUNB, NEUROD1, CHAMP1, TAL1, MAX, GATA1, MTA1, ZNF143, CEBPG, ZNF592, GFI1B, NR2F2, ZKSCAN8, ZNF83, NR2F1, TP53, PKNOX1, NFKB1, BHLHE40, ZBTB40, RB1, MYNN, NCOR1, RNF2, JUND, ILF3, BRD4, CUX1, MAZ, MEF2D, ZNF24, ADNP, AHR
  • Target gene symbol (double-evidenced CRMs): MRPS6,AP000311.1,SLC5A3,ITSN1,RCAN1,ATP5PO,SMIM11A
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 5
  • Number of somatic mutations (non-coding): 5
  • Related genes and loops
  • Related gene: ENSG00000249209, ENSG00000205726, ENSG00000241837, ENSG00000243927, ENSG00000198743, ENSG00000205670, ENSG00000159200,
  • Related loop: chr21:33700000-33725000~~chr21:34100000-34125000, chr21:33775000-33800000~~chr21:34100000-34125000, chr21:33900000-33925000~~chr21:34100000-34125000, chr21:33922677-33925654~~chr21:34108278-34109481, chr21:34100000-34125000~~chr21:34200000-34225000, chr21:34100000-34125000~~chr21:34325000-34350000, chr21:34100000-34125000~~chr21:34350000-34375000, chr21:34100000-34125000~~chr21:34600000-34625000,
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