- Basic information
- CohesinDB ID: CDBP00417626
- Locus: chr21-34113242-34114585
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Data sourse: ENCSR000BLD, ENCSR000BLY, ENCSR404BPV, ENCSR879KXD, GSE206145, ENCSR153HNT, ENCSR198ZYJ, ENCSR000ECS
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Cell type: RPE, H1-hESC, Neurons-H1, HeLa-S3, SK-N-SH, K-562
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: Mau2,SMC3,Rad21,SA1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 58%,
"7_Enh": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NANOG, POU2F2, HDAC1, NKX2-2, PAF1, SOX2, TEAD4, ZNF317, NFATC1, FOXA1, PBX2, ERG2, HOXB13, ERG, RELA, NEUROD1, ZNF148, ONECUT1, RUNX2, ZFP64, RFX1, GATA4, CHD7, RAD21, GRHL3, PBX4, RXRA, GATA3, GABPA, STAT3, PBX3, MZF1, FOXJ2, GATA1, NKX3-1, RCOR1, VDR, KLF4, CEBPB, TRIM28, CREB1, PIAS1, TP53, PKNOX1, ELF3, CTCF, RBM22, EP300, BAF155, TCF12, HNF4A, AR, SPI1, REST, ZBTB7A, GATA2, ZNF479, ZNF146, SIX2, FLI1, ASH2L, BRD4, FOXP1, SMC3
- Target gene symbol (double-evidenced CRMs): ATP5PO,ITSN1,AP000311.1,SMIM11A,RCAN1,MRPS6
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 1
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000249209,
ENSG00000205726,
ENSG00000241837,
ENSG00000243927,
ENSG00000205670,
ENSG00000159200,
- Related loop:
chr21:33700000-33725000~~chr21:34100000-34125000,
chr21:33775000-33800000~~chr21:34100000-34125000,
chr21:33900000-33925000~~chr21:34100000-34125000,
chr21:33922677-33925654~~chr21:34108278-34109481,
chr21:34100000-34125000~~chr21:34200000-34225000,
chr21:34100000-34125000~~chr21:34325000-34350000,
chr21:34100000-34125000~~chr21:34350000-34375000,
chr21:34100000-34125000~~chr21:34600000-34625000,