- Basic information
- CohesinDB ID: CDBP00417630
- Locus: chr21-34125736-34127059
-
Data sourse: GSE67783, GSE111913, ENCSR000HPG, ENCSR404BPV, GSE206145, GSE85526, ENCSR198ZYJ, ENCSR153HNT, GSE165895
-
Cell type: RPE, HEKn, Neurons-H1, RT-112, IMR-90, K-562, HSPC, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.911
- Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"4_Tx": 34%,
"5_TxWk": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: RBM22, FOXA1, HNF4A
- Target gene symbol (double-evidenced CRMs): MRPS6,AP000311.1,ITSN1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 3
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000249209,
ENSG00000205726,
ENSG00000243927,
- Related loop:
chr21:33675000-33700000~~chr21:34125000-34150000,
chr21:33700000-33725000~~chr21:34100000-34125000,
chr21:33775000-33800000~~chr21:34100000-34125000,
chr21:33900000-33925000~~chr21:34100000-34125000,
chr21:33975000-34000000~~chr21:34125000-34150000,
chr21:34100000-34125000~~chr21:34200000-34225000,
chr21:34100000-34125000~~chr21:34325000-34350000,
chr21:34100000-34125000~~chr21:34350000-34375000,
chr21:34100000-34125000~~chr21:34600000-34625000,
chr21:34125000-34150000~~chr21:34225000-34250000,
chr21:34125000-34150000~~chr21:34250000-34275000,
chr21:34125000-34150000~~chr21:34325000-34350000,
chr21:34125000-34150000~~chr21:34625000-34650000,
chr21:34126294-34127644~~chr21:34200972-34203070,
chr21:34128276-34130379~~chr21:34200926-34203224,
chr21:34128540-34130047~~chr21:34201503-34202809,
chr21:34128593-34130330~~chr21:34201154-34203236,
chr21:34128593-34130330~~chr21:34351015-34352657,