- Basic information
- CohesinDB ID: CDBP00417635
- Locus: chr21-34135432-34136514
-
Data sourse: GSE67783, GSE86191, GSE116868, GSE206145, GSE206145-NatGen2015, ENCSR153HNT
-
Cell type: RPE, Fibroblast, HCT-116, MB157, K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: Mau2,SA1,Rad21,SMC1
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"5_TxWk": 56%,
"4_Tx": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: GLIS1, POU2F2, PAF1, ZFX, ZNF600, XBP1, SMAD3, ZBTB48, WT1, YY1, RELA, ZNF384, ATF3, MYC, ZNF362, ZNF184, ZIC2, HIF1A, NKX2-1, STAT3, MAX, TP63, ZNF143, MED1, NCOA3, ELF1, EZH2, TP53, OCA2, TP73, ESR1, ZNF22, JUN, ZHX2, CTCF, RBM22, HSF1, BRD4, MAZ, TEAD4, STAG1
- Target gene symbol (double-evidenced CRMs): AP000311.1,ITSN1,MRPS6
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 6
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000249209,
ENSG00000205726,
ENSG00000243927,
- Related loop:
chr21:33675000-33700000~~chr21:34125000-34150000,
chr21:33975000-34000000~~chr21:34125000-34150000,
chr21:34125000-34150000~~chr21:34225000-34250000,
chr21:34125000-34150000~~chr21:34250000-34275000,
chr21:34125000-34150000~~chr21:34325000-34350000,
chr21:34125000-34150000~~chr21:34625000-34650000,
chr21:34133133-34135105~~chr21:34242552-34244759,
chr21:34133158-34135052~~chr21:34201091-34202966,