- Basic information
- CohesinDB ID: CDBP00417638
- Locus: chr21-34143034-34144103
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Data sourse: ENCSR230ZWH, GSE67783, GSE86191, GSE111913, ENCSR153HNT, ENCSR917QNE
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Cell type: HCT-116, RT-112, K-562, Liver, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"4_Tx": 42%,
"5_TxWk": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, FOSL1, ZNF425, BRD1, ZSCAN5D, MYCN, ZNF263, BRD3, KDM4C, ZFX, NFATC1, XBP1, PAF1, WT1, ZBTB48, SIN3A, TET2, ZBTB33, LEO1, TWIST1, MPHOSPH8, RELA, ATF3, MYC, RAD21, SP140, GRHL3, RXRA, PRDM9, APC, XRCC5, ZNF449, SMARCB1, CHD1, ZNF143, SUPT5H, AGO2, MED1, NR2F2, ELF1, PML, SCRT2, RBM39, KLF6, EZH2, ESR1, OCA2, TBX5, MYOD1, CTCF, RBM22, MAFK, SPI1, SP1, AR, PAX3-FOXO1, RXR, GATA2, ZNF479, FLI1, ZBTB26, HSF1, NOTCH3, BRD4, SCRT1, NCOR1, FOXP1, MYNN, MAZ, HCFC1R1, MRTFB, SMC3, STAG1, EED
- Target gene symbol (double-evidenced CRMs): ITSN1,MRPS6,AP000311.1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 8
- Related genes and loops