- Basic information
- CohesinDB ID: CDBP00417639
- Locus: chr21-34144341-34145170
-
Data sourse: GSE206145-GSE177045, GSE67783, ENCSR153HNT, GSE86191
-
Cell type: K-562, MCF-7, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Mau2,SA1,Rad21
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"8_ZNF/Rpts": 30%,
"5_TxWk": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: RUNX1, FOSL1, ZNF425, BRD1, ZSCAN5D, MYCN, ZNF263, BRD3, KDM4C, ZFX, NFATC1, XBP1, PAF1, WT1, ZBTB48, SIN3A, TET2, ZBTB33, LEO1, TWIST1, MPHOSPH8, RELA, ATF3, MYC, RAD21, SP140, GRHL3, RXRA, PRDM9, APC, XRCC5, ZNF449, SMARCB1, CHD1, ZNF143, SUPT5H, AGO2, MED1, NR2F2, ELF1, PML, SCRT2, RBM39, KLF6, EZH2, ESR1, OCA2, TBX5, MYOD1, CTCF, RBM22, MAFK, SPI1, SP1, AR, PAX3-FOXO1, RXR, GATA2, ZNF479, FLI1, ZBTB26, HSF1, NOTCH3, BRD4, SCRT1, NCOR1, FOXP1, MYNN, MAZ, HCFC1R1, MRTFB, SMC3, STAG1, EED
- Target gene symbol (double-evidenced CRMs): MRPS6,AP000311.1,ITSN1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops
- Related gene:
ENSG00000249209,
ENSG00000205726,
ENSG00000243927,
- Related loop:
chr21:33675000-33700000~~chr21:34125000-34150000,
chr21:33675000-33700000~~chr21:34150000-34175000,
chr21:33975000-34000000~~chr21:34125000-34150000,
chr21:34125000-34150000~~chr21:34225000-34250000,
chr21:34125000-34150000~~chr21:34250000-34275000,
chr21:34125000-34150000~~chr21:34325000-34350000,
chr21:34125000-34150000~~chr21:34625000-34650000,
chr21:34150000-34175000~~chr21:34250000-34275000,
chr21:34150000-34175000~~chr21:34325000-34350000,
chr21:34150000-34175000~~chr21:34525000-34550000,
chr21:34150000-34175000~~chr21:34600000-34625000,
chr21:34150000-34175000~~chr21:34650000-34675000,
chr21:34150000-34175000~~chr21:42625000-42650000,