- Basic information
- CohesinDB ID: CDBP00417640
- Locus: chr21-34146657-34147614
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Data sourse: GSE67783, GSE86191, GSE111913, GSE206145, GSE206145-NatGen2015
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Cell type: RPE, Fibroblast, HCT-116, RT-112, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SA2,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 49%,
"15_Quies": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, TRP47, FOXA2, MYCN, THAP1, PAF1, NFATC1, SP140, ESR1, ZNF429, WT1, ZBTB48, FOXA1, SETDB1, MAZ, RBM22, TFAP2C
- Target gene symbol (double-evidenced CRMs): ITSN1,MRPS6,AP000311.1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 7
- Related genes and loops
- Related gene:
ENSG00000249209,
ENSG00000205726,
ENSG00000243927,
- Related loop:
chr21:33675000-33700000~~chr21:34125000-34150000,
chr21:33675000-33700000~~chr21:34150000-34175000,
chr21:33975000-34000000~~chr21:34125000-34150000,
chr21:34125000-34150000~~chr21:34225000-34250000,
chr21:34125000-34150000~~chr21:34250000-34275000,
chr21:34125000-34150000~~chr21:34325000-34350000,
chr21:34125000-34150000~~chr21:34625000-34650000,
chr21:34150000-34175000~~chr21:34250000-34275000,
chr21:34150000-34175000~~chr21:34325000-34350000,
chr21:34150000-34175000~~chr21:34525000-34550000,
chr21:34150000-34175000~~chr21:34600000-34625000,
chr21:34150000-34175000~~chr21:34650000-34675000,
chr21:34150000-34175000~~chr21:42625000-42650000,