- Basic information
- CohesinDB ID: CDBP00417643
- Locus: chr21-34153764-34154473
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Data sourse: GSE105028, GSE67783, ENCSR153HNT, GSE206145
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Cell type: K-562, HSPC, RPE, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 56%,
"5_TxWk": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, TRP47, BRD1, ZSCAN5D, MYCN, ZNF263, ZFX, XBP1, SMAD3, ZBTB48, ZSCAN5A, WT1, ERG, YY1, MYC, THAP1, SP140, ARNT, GRHL3, NKX2-1, GABPA, AGO2, MITF, SNRNP70, PLAG1, MAF, CEBPB, ELF1, TRIM28, NR2F1, EZH2, ZNF3, CTCF, RBM22, E2F4, FLI1, NOTCH3, BRD4, MAZ, SMC3, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): CLIC6,RCAN1,ITSN1,AP000311.1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 5
- Related genes and loops
- Related gene:
ENSG00000249209,
ENSG00000205726,
ENSG00000159200,
ENSG00000159212,
- Related loop:
chr21:33675000-33700000~~chr21:34125000-34150000,
chr21:33675000-33700000~~chr21:34150000-34175000,
chr21:33975000-34000000~~chr21:34125000-34150000,
chr21:34125000-34150000~~chr21:34225000-34250000,
chr21:34125000-34150000~~chr21:34250000-34275000,
chr21:34125000-34150000~~chr21:34325000-34350000,
chr21:34125000-34150000~~chr21:34625000-34650000,
chr21:34150000-34175000~~chr21:34250000-34275000,
chr21:34150000-34175000~~chr21:34325000-34350000,
chr21:34150000-34175000~~chr21:34525000-34550000,
chr21:34150000-34175000~~chr21:34600000-34625000,
chr21:34150000-34175000~~chr21:34650000-34675000,
chr21:34150000-34175000~~chr21:42625000-42650000,