- Basic information
- CohesinDB ID: CDBP00417647
- Locus: chr21-34161095-34161474
-
Data sourse: GSE206145, GSE67783, ENCSR153HNT
-
Cell type: K-562, HSPC, RPE
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 47%,
"9_Het": 36%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: FOXO1, NFIA, PGR, ZNF660, HMGN3, MEIS2, NME2, XBP1, FOXA1, RBFOX2, PBX2, UBTF, ZFHX2, ATF3, NFIC, THAP1, ATF4, MECOM, TP63, MITF, ELF1, TRIM28, ZNF121, ESR1, MLL, OCA2, USF2, CTCF, TCF12, JUN, DPF2, E2F6, TRIM24, TEAD4, EHMT2, TFAP2C, POU2F2, CHD8, BRD1, ZSCAN5D, ZNF263, MYCN, POU5F1, BRD3, TOP2A, CTBP1, ZNF317, ZBTB17, ZBTB48, ZSCAN5A, MTA2, MLLT3, SRF, DDX5, HNF4G, PAX6, ERG, ASCL1, OGG1, MYC, SMARCA4, ARID1B, RAD21, LHX2, GRHL3, RXRA, NKX3-1, PRDM14, RCOR1, NR2F6, NR3C1, CEBPB, EZH2, GRHL2, EBF3, SPI1, ZNF257, HDAC2, GATA2, ZNF644, MXD3, FLI1, RUNX1, SMC1A, CEBPA, HDAC1, SIRT6, CRY1, ZNF335, ZFX, SMAD3, TET2, TWIST1, PRDM10, RARA, ZNF384, ZBTB2, RUNX2, CDK6, GR, PBX4, ARNT, SOX11, ATF2, ZEB2, HMBOX1, SMAD4, ETV6, CBFA2T3, CDK8, MED1, CEBPD, ZNF680, PIAS1, ZNF3, ZNF22, USF1, BCL11A, SP1, HNF4A, ARID2, REST, ZNF479, ZBTB7A, ASH2L, CTBP2, AATF, SMC3, NCOR2, STAG1, SKI, TRP47, CBFA2T2, FOXA2, TBL1X, AGO1, MEIS1, ZNF692, WT1, ZBTB33, HOXB13, YY1, RELA, NEUROD1, SP140, HIF1A, OTX2, ZNF519, TAL1, MAX, ZNF143, AGO2, GATA1, HAND2, PLAG1, CEBPG, NCOA3, NR2F2, NEUROG2, NR2F1, TP53, PKNOX1, ZBTB6, ZNF334, PHOX2B, AR, ZNF324, HEXIM1, HSF1, RNF2, NOTCH3, BRD4, JUND, NCOR1, MAZ, TBX2, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): AP000311.1,RCAN1,CLIC6,ITSN1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000249209,
ENSG00000205726,
ENSG00000159200,
ENSG00000159212,
- Related loop:
chr21:33675000-33700000~~chr21:34150000-34175000,
chr21:34150000-34175000~~chr21:34250000-34275000,
chr21:34150000-34175000~~chr21:34325000-34350000,
chr21:34150000-34175000~~chr21:34525000-34550000,
chr21:34150000-34175000~~chr21:34600000-34625000,
chr21:34150000-34175000~~chr21:34650000-34675000,
chr21:34150000-34175000~~chr21:42625000-42650000,