- Basic information
- CohesinDB ID: CDBP00417649
- Locus: chr21-34166374-34166733
-
Data sourse: GSE105028, ENCSR153HNT, GSE86191, GSE206145
-
Cell type: K-562, HCT-116, RPE, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: NIPBL,SA1,Rad21
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"9_Het": 65%,
"8_ZNF/Rpts": 30%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: RUNX1, JARID2, ZNF394, CBX5, CBX1, CBX3, POU5F1, MYCN, MTA3, ID3, ZFX, XBP1, ZBTB48, WT1, TBP, MPHOSPH8, ZNF549, YY1, NOTCH1, ZNF626, ZNF280A, ZNF510, ZNF184, ZNF311, ZEB2, ZNF518A, ZNF143, RCOR1, JMJD1C, NCOA3, ZNF558, TRIM28, ZNF680, PIAS1, SETDB1, GABPB1, AR, ZNF324, TRIM24, ZNF280D, MAZ, ZNF528, ZNF350, SMC3, ZNF92, ZNF24, EHMT2, TFAP2C
- Target gene symbol (double-evidenced CRMs): ITSN1,CLIC6,AP000311.1,RCAN1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000249209,
ENSG00000205726,
ENSG00000159200,
ENSG00000159212,
- Related loop:
chr21:33675000-33700000~~chr21:34150000-34175000,
chr21:34150000-34175000~~chr21:34250000-34275000,
chr21:34150000-34175000~~chr21:34325000-34350000,
chr21:34150000-34175000~~chr21:34525000-34550000,
chr21:34150000-34175000~~chr21:34600000-34625000,
chr21:34150000-34175000~~chr21:34650000-34675000,
chr21:34150000-34175000~~chr21:42625000-42650000,