- Basic information
- CohesinDB ID: CDBP00417652
- Locus: chr21-34180822-34181533
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Data sourse: ENCSR000BLD, ENCSR000EEG, ENCSR230ZWH, GSE72082, GSE25021, ENCSR000BLS, GSE105028, ENCSR000ECE, GSE106870, ENCSR917QNE
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Cell type: H1-hESC, Hep-G2, CVI-hiPSC, Liver, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 39%,
"7_Enh": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, HMG20A, SOX2, MEIS2, FOXA1, RBFOX2, RING1B, RXRB, ATF3, CHD7, MITF, MAF, TEAD1, TRIM28, ZNF573, ELF1, LMO2, ESR1, CTCF, BAF155, SOX5, RYBP, TEAD4, GATAD2A, RBPJ, TFAP2C, NANOG, CHD8, BRD1, POU5F1, MYCN, DUX4, ERG, SMARCA4, RAD21, RXRA, XRCC5, SOX10, NKX3-1, PRDM14, MIER3, LEF1, NR2F6, NR3C1, CREB1, EZH2, GRHL2, SPI1, HDAC2, GATA2, ZIM3, CTNNB1, BCL6, SOX13, POU4F2, ERG3, CBX8, ZNF384, GR, ARNT, NRF1, ATF2, PRDM9, SMAD4, CHD1, MED1, TEAD3, ZNF3, C11orf30, NIPBL, SP1, REST, POU2F3, ASH2L, BCOR, FOXP1, FOXA2, RBBP5, MAFF, WT1, HOXB13, KDM1A, YY1, RELA, NEUROD1, BRG1, HIF1A, OTX2, GATA3, MAX, GATA1, CBX2, KLF4, NR2F2, TP53, AR, RNF2, BRD4, CLOCK, ZNF316
- Target gene symbol (double-evidenced CRMs): MRPS6,ATP5PO,ITSN1,AP000311.1,SLC5A3,RCAN1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000249209,
ENSG00000205726,
ENSG00000241837,
ENSG00000243927,
ENSG00000198743,
ENSG00000159200,
- Related loop:
chr21:33900000-33925000~~chr21:34175000-34200000,
chr21:34075000-34100000~~chr21:34175000-34200000,
chr21:34175000-34200000~~chr21:34325000-34350000,
chr21:34175000-34200000~~chr21:34500000-34525000,